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Snyder Lab ResearchInformation on the many exciting projects in the Snyder Lab:Right now this site is in progress, and the information is not up-to-date. Please be patient as these pages are slowly updated. Our laboratory uses global approaches to explore protein function and dissect regulatory networks. Several of our areas of research are:
1. Control of cell division and cell morphology in yeast 2. Characterization of proteomes We have developed a number of novel approaches to characterize protein function in yeast and humans. A novel protein microarray technology was invented for analyzing large numbers of proteins. Nearly all yeast proteins were overexpressed and purified and deposited on a microscope slide. The chips have been used for a variety of applications including interactions with proteins, lipids, DNA and small molecules. Using this technology we have discovered that a metabolic enzyme, Arg5,6 associates with DNA to regulate gene expression in yeast. We are using this technology to develop a protein phosphorylation map for yeast. We are also extending this technology to humans as well as employing other novel methods for analyzing protein function in humans. 3. Analysis of regulatory circuits in yeast |
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