Rosenbaum Lab Publications



Marshall WF, Rosenbaum JL. 2003. Tubulin superfamily: giving birth to triplets Curr. Biol. 13, R55-R56.

Rosenbaum JL. 2002. Intraflagellar Transport [Quick Guide] Curr. Biol. 12,R125.

Rosenbaum JL, Witman GB. 2002. Intraflagellar transport. Nat Rev Mol Cell Biol. 3,813-25.

Marshall W. 2002. Size control in dynamic organelles. Trends Cell Biol. 12,414-9.

Pazour G, Rosenbaum JL. 2002. Intraflagellar transport and cilia-dependent diseases. Trends Cell Biol. 12,551-5.

Pazour GJ, San Agustin JT, Follit JA, Rosenbaum JL, Witman GB. 2002. Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease. Curr Biol. 2002 12,R378-80.

Pazour GJ, Baker SA, Deane JA, Cole DG, Dickert BL, Rosenbaum JL, Witman GB, Besharse JC. 2002. The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance. J Cell Biol. 157,103-13.

Marshall WF, Rosenbaum JL. 2001. Intraflagellar transport balances continuous turnover of outer doublet microtubules: implications for flagellar length control. J. Cell Biol. 155,405-414.

Deane JA, Cole DG, Seeley, ES, Diener, DR, Rosenbaum JL. 2001. Localization of the intraflagellar transport protein IFT52 identifies the transitional fibers of the basal bodies as the docking site for IFT particles. Curr. Biol. 11,1586-1590.

Marshall WF. 2001. Centrioles take center stage. Curr. Biol. 11,R487-R496.

Marshall WF, Vucica Y, and Rosenbaum JL. 2001. Kinetics and regulation of de novo centriole assembly: implications for the mechanism of centriole duplication. Curr. Biol. 11,308-317.

Qin H, Rosenbaum JL, Barr MM. 2001. An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons. Curr. Biol. 11,457-461.

Yang P, Diener DR, Rosenbaum JL, Sale WS. 2001. Localization of calmodulin and dynein light chain LC8 in flagellar radial spokes. J. Cell Biol. 153,1315-1326.

Roush-Gaillard A, Diener DR, Rosenbaum JL, Sale WS. 2001. Flagellar radial spoke protein 3 is an A-kinase anchoring protein (AKAP). J. Cell Biol. 153,443-448.

Rosenbaum JL. 2000. Functions for tubulin modifications at last. Curr. Biol. 10,R801-803.

Marshall WF, Rosenbaum JL. 2000. Are there nucleic acids in the centrosome? Curr. Top. Dev. Biol. 49,187-205.

Pazour GJ, Dickert BL, Vucica Y, Seeley ES, Rosenbaum JL, Witman GB, and Cole DG. 2000. Chlamydomonas IFT88 and its mouse homologoue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J. Cell Biol. 151,709-7118.

Marshall WF, Rosenbaum JL. 2000. How centrioles work: lessons from green yeast. Curr. Opin. Cell Biol. 12,119-125.

Marshall WF, Rosenbaum JL. 1999. Cell division: the renaissance of the centriole. Curr. Biol. 9,R218-R220.

Rosenbaum JL, Cole DG, and Diener DR. 1999. Intraflagellar transport: the eyes have it. J. Cell Biol. 144,385-388.

Cole DG, Diener DR, Himelblau AL, Beech PL, Fuster JC, and Rosenbaum JL. 1998. Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons. J. Cell Biol. 141,993-1008.

Kozminski KG, Forscher P, and Rosenbaum JL. 1998. Three flagellar motilities in Chlamydomonas unrelated to flagellar beating. Video supplement. Cell Motil. Cytoskeleton 39,347-348.

Beech PL, Pagh-Roehl K, Noda Y, Hirokawa N, Burnside B, and Rosenbaum JL. 1996. Localization of kinesin superfamily proteins to the connecting cilium of fish photoreceptors. J. Cell Sci. 109,889-97.

Kozminski KG, Beech PL, and Rosenbaum JL. 1995. The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane. J. Cell Biol. 131,1517-27.

Bernstein M, Beech PL, Katz SG, and Rosenbaum JL. 1994. A new kinesin-like protein (Klp1) localized to a single microtubule of the Chlamydomonas flagellum. J. Cell Biol. 125,1313-26.

Johnson KA, Haas MA, and Rosenbaum JL. 1994. Localization of a kinesin-related protein to the central pair apparatus of the Chlamydomonas reinhardtii flagellum. J. Cell Sci. 107,1551-6.

Diener DR, Ang LH, and Rosenbaum JL. 1993. Assembly of flagellar radial spoke proteins in Chlamydomonas: identification of the axoneme binding domain of radial spoke protein 3. J. Cell Biol. 123,183-90.

Kozminski KG, Diener DR, and Rosenbaum JL. 1993. High level expression of nonacetylatable alpha-tubulin in Chlamydomonas reinhardtii. Cell Motil. Cytoskeleton 25,158-70.

Kozminski KG, Johnson KA, Forscher P, and Rosenbaum JL. 1993. A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc. Natl. Acad. Sci. USA. 90,5519-23.

Curry AM and Rosenbaum JL. 1993. Flagellar radial spoke: a model molecular genetic system for studying organelle assembly. Cell Motil. Cytoskeleton 24,224-43.

Johnson KA and Rosenbaum JL. 1992. Polarity of flagellar assembly in Chlamydomonas. J. Cell Biol. 119,1605-11.

Johnson KA and Rosenbaum JL. 1992. Replication of basal bodies and centrioles. Curr. Opin. Cell Biol. 4,80-5.

Curry AM, Williams BD, and Rosenbaum JL. 1992. Sequence analysis reveals homology between two proteins of the flagellar radial spoke. Mol. Cell. Biol. 12,3967-77.

Johnson KA and Rosenbaum JL. 1990. The basal bodies of Chlamydomonas reinhardtii do not contain immunologically detectable DNA. Cell 62,615-9.

Diener DR, Curry AM, Johnson KA, Williams BD, Lefebvre PA, Kindle KL, and Rosenbaum JL. 1990. Rescue of a paralyzed-flagella mutant of Chlamydomonas by transformation. Proc. Natl. Acad. Sci. USA. 87,5739-43.

Williams BD, Velleca MA, Curry AM, and Rosenbaum JL. 1989. Molecular cloning and sequence analysis of the Chlamydomonas gene coding for radial spoke protein 3: flagellar mutation of pf-14 is an ochre allele. J. Cell Biol. 109,235-245.

Baker EJ, Diener DR, and Rosenbaum JL. 1989. Accelerated poly(A) loss on alpha-tubulin mRNAs during protein synthesis inhibition in Chlamydomonas. J. Mol. Biol. 207,771-781.

Bandziulis RA and Rosenbaum JL. 1988. Novel control elements in the alpha-1 tubulin gene promoter from Chlamydomonas reinhardii. Mol. Gen. Genet. 214,204-212.

Williams BD, Mitchell DR, and Rosenbaum JL. 1986. Molecular cloning and expression of flagellar radial spoke and dynein genes of Chlamydomonas. J. Cell Biol. 103,1-11.

Baker EJ, Keller LR, Schloss JA, and Rosenbaum JL. 1986. Protein synthesis is required for rapid degradation of tubulin mRNA and other deflagellation-induced RNAs in Chlamydomonas reinhardi. Mol. Cell. Biol. 6,54-61.

Maruta H, Greer K, and Rosenbaum JL. 1986. The acetylation of alpha-tubulin and its relationship to the assembly and disassembly of microtubules. J. Cell Biol. 103,571-579.

Mitchell DR and Rosenbaum JL. 1986. Protein-protein interactions in the 18S ATPase of Chlamydomonas outer dynein arms. Cell Motil. Cyt. 6,510-520.

Lefebvre PA and Rosenbaum JL. 1986. Regulation of the synthesis and assembly of ciliary and flagellar proteins during regeneration. Annu. Rev. Cell Biol. 2,517-546.

Mitchell DR and Rosenbaum JL. 1985. A motile Chlamydomonas flagellar mutant that lacks outer dynein arms. J. Cell Biol. 100,1228-1234.

L'Hernault SW and Rosenbaum JL. 1985. Chlamydomonas alpha-tubulin is posttranslationally modified by aceytlation on the epsilon-amino group of a lysine. Biochemistry 24,473-478.

Greer K, Maruta H, L'Hernault SW, and Rosenbaum JL. 1985. Alpha-tubulin acetylate activity in isolated Chlamydomoans flagella. J. Cell Biol. 101,2081-2084.

L'Hernault SW and Rosenbaum JL. 1985. Reveral of the posttranslational modification on Chlamydomonas flagellar alpha-tubulin occurs during flagellar resorption. J. Cell Biol. 100,457-462.

Keller LR, Schloss JA, Silflow CD, and Rosenbaum JL. 1984. Transcription of alpha- and beta-tubulin genes in vitro in isolated Chlamdyomonas reinhardi nuclei. J. Cell Biol. 98,1138-1143.

Baker EJ, Schloss JA, and Rosenbaum JL. 1984. Rapid changes in tubulin RNA synthesis and stabilitiy induced by deflagellation in Chlamydomonas. J. Cell Biol. 99,2074-2081.

Schloss JA, Silflow CD, and Rosenbaum JL. 1984. mRNA abudance changes during flagellar regeneration in Chlamydomonas reinhardtii. Mol. Cell. Biol. 4,424-434.

McKeithan TW and Rosenbaum JL. 1984. The biochemistry of microtubules. A review. Cell Muscle Motil. 5,255-288.

McKeithan TW, Lefebvre PA, Silflow CD, and Rosenbaum JL. 1983. Multiple forms of tubulin in Polytomella and Chlamydomonas: evidence for a precursor of flagellar alpha-tubulin. J. Cell Biol. 96,1056-1063.

L'Hernault SW and Rosenbaum JL. 1983. Chlamydomonas alpha-tubulin is posttranslationally modified in the flagella during flagellar assembly. J. Cell Biol. 97,258-263.

Clark TG and Rosenbaum JL. 1982. Pigment particle translocation in detergent-permeabilized melanophores of Fundulus heteroclitus. Proc. Natl. Acad. Sci. U.S.A. 79,4655-4659.

Silflow CD, Lefebvre PA, McKeithan TW, Schloss JA, Keller LR, and Rosenbaum JL. 1982. Expression of flagellar protein genes during flagellar regeneration in Chlamydomonas. Cold Spring Harg. Symp. Quant. Biol. 46,157-169.

Sloboda RD, Van Blaricom G, Creasey WA, Rosenbaum JL, and Malawista SE. 1982. Griseofulvin: association with tubulin and inhibition of in vitro microtubule assembly. Biochem. Biophys. Res. Comm. 105,882-888.

Silflow CD and Rosenbaum JL. 1981. Multiple alpha- and beta-tubulin genes in Chlamydomonas and regulation of tubulin mRNA levels after deflagellation. Cell 24,81-88.

Haimo LT and Rosenbaum JL. 1981. Dynein binding to microtubules containing microtubule-associated proteins. Cell Motil. 1,499-515.

McKeithan TW and Rosenbaum JL. 1981. Multiple forms of tubulin in the cytoskeleton and flagellar microtubules of Polytomella. J. Cell Biol. 91,352-360.

Jarvik JW and Rosenbaum JL. 1980. Oversized flagellar membrane protein in paralyzed mutants of Chlamydomonas reinhardtii. J. Cell Biol. 85,258-272.

Lefebvre PA, Silflow CD, Wieben ED, and Rosenbaum JL. 1980. Increased levels of mRNAs for tubulin and other flagellar proteins after amputation or shortening of Chlamydomonas flagella. Cell 20,469-477.

Clark TG and Rosenbaum JL. 1979. An actin filament matrix in hand-isolated nuclei of X. laevis oocytes. Cell 18,1101-1108.

Kim H, Binder LI, and Rosenbaum JL. 1979. The periodic association of MAP2 with brain microtubules in vitro. J. Cell Biol. 80,266-276.

Sloboda RD and Rosenbaum JL. 1979. Decoration and stabilization of intact, smooth-walled microtubules with microtubule-associated proteins. Biochemistry 18,48-55.

Haimo LT, Telzer BR, and Rosenbaum JL. 1979. Dynein binds to and crossbridges cytoplasmic microtubules. Proc. Natl. Acad. Sci. U.S.A. 76,5759-5763.

Telzer BR and Rosenbaum JL. 1979. Cell cycle-dependent, in vitro assembly of microtubules onto pericentriolar material of HeLa cells. J. Cell Biol. 81,484-497.

Lefebvre PA, Nordstrom SA, Moulder JE, and Rosenbaum JL. 1978. Flagellar elongation and shortening in Chlamydomonas. IV. Effects of flagellar detachment, regeneration, and resorption on the induction of flagellar protein synthesis. J. Cell Biol. 78,8-27.

Binder LI and Rosenbaum JL. 1978. The in vitro assembly of flagellar outer doublet tubulin. J. Cell Biol. 79,500-515.

Dentler WL and Rosenbaum JL. 1977. Flagellar elongation and shortening in Chlamydomonas. III. structures attached to the tips of flagellar microtubules and their relationship to the directionality of flagellar microtubule assembly. J. Cell Biol. 74,747-759.

Sloboda RD, Dentler WL, and Rosenbaum JL. 1976. Microtubule-associated proteins and the stimulation of tubulin assembly in vitro. Biochemistry 15,4497-4505.

Bloodgood RA and Rosenbaum JL. 1976. Initiation of brain tubulin assembly by a high molecular weight flagellar protein factor. J. Cell Biol. 71,322-331.

Telzer BR, Moses JL, and Rosenbaum JL. 1975. Assembly of microtubules onto kinetochores of isolated mitotic chromosomes of HeLa cells. Proc. Natl. Acad. Sci. U.S.A. 18,48-55.

Sloboda RD, Rudolph SA, Rosenbaum JL, and Greegard P. 1975. Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein. Proc. Natl. Acad. Sci. U.S.A. 72,177-181.

Binder LI, Dentler WL, and Rosenbaum JL. 1975. Assembly of chick brain tubulin onto flagellar microtubules from Chlamydomonas and sea urchin sperm. Proc. Natl. Acad. Sci. U.S.A. 72,1122-1126.

Rosenbaum JL, Binder LI, Granett S, Dentler WL, Snell W, Sloboda R, and Haimo L. 1975. Directionality and rate of assembly of chick brain tubulin onto pieces of neurotubules, flagellar axonemes, and basal bodies. Ann. NY. Acad. Sci. 253,147-177.

Snell WJ, Dentler WL, Haimo LT, Binder LI, and Rosenaum JL. 1974. Assembly of chick brain tubulin onto isolated basal bodies of Chlamydomonas reinhardi. Science 185,357-360.

Rebhun LI, Rosenbaum J, Lefebvre P, and Smith G. 1974. Reversible restoration of the birefringence of cold-treated, isolated mitotic apparatus of surf clam eggs with chick brain tubulin. Nature 249,113-115.

Witman GB, Carlson K, and Rosenbaum JL. 1972. Chlamydomonas flagella. II. The distribution of tubulins 1 and 2 in the outer doublet microtubules. J. Cell Biol. 54,540-555.

Witman GB, Carlson K, Berliner J, and Rosenbaum JL. 1972. Chlamydomonas flagella. I. Isolation and electrophoretic analysis of microtubules, matrix, membranes, and mastigonemes. J. Cell Biol. 54,507-539.

Olmsted JB, Witman GB, Carlson K, and Rosenbaum JL. 1971. Comparison of the microtubule proteins of neuroblastoma cells, brain, and Chlamydomonas flagella. Proc. Natl. Acad. Sci. U.S.A. 68,2273-2277.

Coyne B and Rosenbaum JL. 1970. Flagellar elongation and shortening in Chlamydomonas. II. Re-utilization of flagellar proteins. J. Cell Biol. 47,777-781.

Rosenbaum JL and Carlson K. 1969. Cilia regeneration in Tetrahymena and its inhibition by colchicine. J. Cell Biol. 40,415-425.

Rosenbaum JL, Moulder JE, and Ringo DL. 1969. Flagellar elongation and shortening in Chlamydomonas. I. The use of cycloheximide and colchicine to study the synthesis and assembly of flagellar proteins. J. Cell Biol. 41,600-619.

Rosenbaum JL and Child F. 1967. Flagellar regeneration in protozoan flagellates. J. Cell Biol. 34,345-364.


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