Rebecca Muhle
Resident, Program in Integrated Child, Adolescent and Adult Psychiatry
(joint with Matthew State)
Contact: Rebecca.Muhle-AT-yale.edu
Rebecca spent her childhood in the eastern and southern United States and Canada, then moved overseas as a teenager and lived in Saudi Arabia, Greece, and Switzerland. She returned to the States for college, and obtained a B.A. in Psychology from the University of Texas at Austin. She joined Dr. Ronald DePinho' s lab at the Albert Einstein College of Medicine following graduation, examining protein binding partners of the tumor suppressor protein Sin3, then completed studies of infection-induced preterm labor using a murine model in the laboratory of Dr. Emmet Hirsch at Columbia University. Rebecca obtained her M.D. at Albert Einstein, as well as a Ph.D. in Microbiology and Immunology with her mentor, Dr. David A. Fidock (now at Columbia University). Her thesis detailed the development of new molecular methods and tools to better elucidate the in situ genetic regulation of antigenically variant var genes in the malaria parasite Plasmodium falciparum. While completing her medical training, she pursued her interest in autism spectrum disorders by co-authoring a paper with Dr. Isabel Rapin, a renowned pediatric neurologist. Her interest in psychiatry continued to grow during her clinical rotations, and she was awarded the Maurice Greenhill Memorial Award in Psychiatry upon graduation in 2010. She is currently enrolled in the Albert J. Solnit Integrated Adult and Child & Adolescent Psychiatry Residency Training Program of the Yale Child Study Center, a 6-year program designed to foster the research interests of young child psychiatrists by providing protected time for scientific pursuits. Rebecca’s project is the outgrowth of collaboration between Dr. Matthew State and Dr. Noonan, and it endeavors to uncover the regulatory targets of transcription factors and chromatin modifiers identified via whole-exome screens to be associated with a risk of autism. Once target sites are pinpointed, neighboring genes will be identified and screened for involvement in the pathogenesis of autism. Rebecca also enjoys spending time with her husband, their two boys, and the family cat, Vitamin.
The Noonan Lab
