PUBLICATIONS
- Blaho, D. V. and Miranker, A. D. (2009) Deleniating the conformational elements responsible for Cu(II)-induced oligomerization of beta-2 Microglobulin. Biochemistry 48: 6610-6617. PDF
- Hebda, J. A. and Miranker, A. D. (2009)
The Interplay of Catalysis and Toxicity by Amyloid Intermediates on Lipid Bilayers: Insights from Type II Diabetes. Annu Rev Biophys 38: 125-52. PDF
- Calabrese, M. F. and Mirakner, A. D. (2009) Metal binding sheds light on mechanism of amyloid assembly. Prion 3 (1): 1-4. PDF
- Knight, J. D., Williamson, J. A. and Miranker, A. D. (2008) Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin. Protein Sci. 17 (10): 1850-6. PDF
- Calabrese, M. F., et. al. (2008) A regulatable switch mediates self-association in an immunoglobulin fold. NSMB 15: 965-71. PDF
- Koo, B. W. Hebda, J. A. and Miranker, A.D. (2008) Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide. Protein Eng Des Sel. 21 (3): 147-54. PDF
- Jaswal, S. S. and Miranker, A. D. (2007) Scope and utility of hydrogen exchange as a tool for mapping landscapes. Protein Sci. 16 (11): 2378-90. PDF
- Ruschak, A.R. and Miranker, A.D. (2007) Fiber-dependent amyloid formation as catalysis of an existing reaction pathway. PNAS 104: 12341-6. PDF
- Calabrese, M.F. and Miranker, A.D. (2007) Formation of a Stable Oligomer of beta-2 Microglobulin Requires only Transient Encounter with Cu(II). JMB 367: 1-7. PDF
- Williamson, J.A., and Miranker, A.D. (2007) Direct detection of transient alpha-helical states in islet amyloid polypeptide. Protein Sci 16: 110-117. PDF
- Knight, J. D., Hebda, J. A., Miranker, A. D. (2006) Conserved and cooperative assembly of membrane-bound states of islet amyloid polypeptide. Biochemistry, 45(31):9496-508. PDF
- Eakin, C. M., Berman, A. J., Miranker, A. D. (2006) A native to amyloidogenic transition regulated by a backbone trigger. NSMB 13:202-208. PDF
-
Eakin, C. M. and Miranker, A.D. (2005) From chance to frequent encounters: Origins of beta 2-microglobulin fibrillogenesis. Biochim. Biophys Acta 1753:92-9 PDF
- Miranker A. D. (2005) Quantitative Measurement of Fibrillogenesis by Mass Spectrometry.
Methods Mol Biol 299:185-194. Link
- Miranker, A.D. (2005). Structural biology - Fibres hinge on swapped domains. Nature 437:197-198. PDF
- Koo B.W., Miranker A.D. (2005). Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid. Protein Science 14:231-239. PDF
- Knight, J.D. and Miranker, A.D. (2004). Phospholipid catalysis of diabetic amyloid assembly. J. Mol. Biol. 341:1175-1187. PDF
- Miranker A.D. (2004). Unzipping the mysteries of amyloid fiber formation. Proc. Natl. Acad. Sci. (USA) 101:4335-4336. PDF
- Eakin C. M., Attenello F.J. , Morgan C.J. and Miranker A.D. (2004). Oligomeric assembly of native-like precursors precedes amyloid formation by B-2 Microglobulin. Biochemistry 43:7808-7815. PDF
- Larson, J.L. and Miranker, A.D. (2004). The mechanism of insulin action on islet amyloid polypeptide fiber formation. J. Mol. Biol. 335:221-31. PDF
- Eakin, C., Knight, J., Morgan, C., Gelfand, M. and Miranker. A.D. (2002) Formation of a copper specific binding site in non-native states of Beta-2-Microglobulin. Biochemistry. 41:10646-10656 PDF
- Padrick, S. and Miranker. A.D. (2002) Islet amyloid: phase partitioning and secondary nucleation are central to the mechanism of firillogenesis. Biochemistry. 41:4694-4703 PDF
- Morgan, C., Gelfand, M., Atreya, C. and Miranker, A. D. (2001) Kidney dialysis-associated amyloidosis: a molecular role for copper in fibril formation J. Mol. Biol. 309:339-345 PDF
- Padrick, S. Miranker, A. D. (2001) Islet amyloid polypeptide: Identification of long range contacts and local order on the fibrillogenesis pathway J. Mol. Biol. 308:783-794 PDF
- Larson, J. L., Ko, E. Miranker, A. D. (2000) Direct measurement of islet amyloid polypeptide fibrillogenesis by mass spectrometry. Protein Science 9:427-431 PDF
- Miranker A. D. (2000). Protein complexes and analysis of their assembly by mass spectrometry Curr Opin Struct Biol 10:601-606 PDF
- Miranker, A. D. (2000). Mass spectrometry of proteins of known mass Proc Natl Acad Sci (USA) 97:14025-70 PDF
- Weber-ban, E. Reid, B.G. Miranker, A.D. Horwich, A. L. (1999). Global unfolding of a substrate protein by the Hsp100 chaperone ClpA. Nature 401:90-93 PDF
- Canet, D., Sunde, M., Last, A. M., Miranker, A., Spencer, A., Robinson, C. V., Dobson, C. M. (1999). Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants. Biochemistry 38:6419-6427. PDF
- Morgan, C. J., Miranker, A. and Dobson, C. M. (1998). Characterization of collapsed states in the early stages of the refolding of hen lysozyme. Biochemistry 37:8473-8480. PDF
- Hooke, S. D., . Eyles, S. J., Miranker, A. D., Radford, S. E., Robinson, C. V., and Dobson, C. M. (1995). Cooperative Elements in Protein Folding Monitored by Electrospray Ionization Mass Spectrometry. JACS 117, 7548-7549. PDF
