 |
Recent Doctoral Dissertations
| Dissertation Title |
Graduate Student |
Adviser(s) |
| May 2012 |
|
|
| Genome-wide mapping and functional Analysis of Copy Number Variation in The Humane Genome |
Rajini Haraksingh |
Michael Snyder |
| Identification and characterization of the ligand for PUNC |
Su Li |
Elke Stein |
| Biochemical Analysis of the Complex Network of Her Dimers During Zebrafish Somitogenesis (Holley Lab) |
Anna Trofka |
Scott Holley |
| Neural crest specification and Pax7 cis-regulation |
Stephanie Vadasz |
Martin Garcia-Castro |
| The Role of Pax7 in Neural Crest Development |
Casey Walsh-Delconte |
Martin Garcia-Castro |
| Neural Crest Induction in the Non-neural Ectodern and The Role of Nfat5 in the Early
Neural Crest Development |
Nathan Yardley |
Garcia-Castro Lab |
| |
|
|
| December 2011 |
|
|
| A Study of MicroRNA Oncogene-Addiction in Lymphoma and MicroRNA Radiosensitizers in Lung Cancer |
Imran Ali Babar |
Frank Slack |
| Investigations of the Role of the Regeneration Epithelium during Axolotl Limb Regeneration |
Leah Jean Campbell |
Craig Crews |
| Involvement of MiRNAs in Crop Development and Differential And Differential Epigenetic Modifications within co-Expression Clusters |
Yeqin Ma |
Xing-Wang Deng |
| Age Associated Defects in AMP-Activated Protein Kinase and Mitochandrial Biogenesis |
Richard Resnick |
Gerald Shulman |
| FGF Signaling in Early Neural In Early Neural Crest Development |
Timothy Stuhlmiller |
Martin Garcia-Castro |
| A novel mechanism of MicroRNA up Regulation n the timing of stem-cell-fate decisions |
Michael Turner |
Frank Slack |
| A Large, Noncoded RNA Confers Alcohol Stress Tolerance in Extremophilic Bacteria |
Jason Wallace |
Braker Lab |
| |
|
|
| May 2011 |
|
|
| Genomic Analysis of the PGC-1alpha Transcriptional Regulatory Network |
Alexandra Charos |
Michael Snyder |
| A Ulp1 Substrate Suggests Roles for the SUMO Pathway in Regulating Inositol Synthesis and Reveals the Significance of the Ulp1 Coiled Coin Domain in Substrate Contact |
Rachel Felberbaum |
Mark Hochstrasser |
| Variation in Transcription Factor Binding Among Humans |
Maya Kasowski |
Sherman Weissman & Michael Snyder |
| DSCAM: Tails of Two Isoforms |
Alice Ly |
Elke Stein |
| Spatial organization of the flow of genetic information in Bacteria |
Paula Montero Llopis |
Christine Jacobs-Wagner |
| Insights into Chromosome Segregation Dynamics in C. crescentus |
Whitman Schofield |
Christine Jacobs-Wagner |
| |
|
|
| December 2010 |
|
|
| The Discovery and Characterization of Novel Riboswitches and Other ncRNA’s |
Tyler Ames |
Ronald Breaker |
| Exploring Complex Noncoding RNAs in Bacteria |
Kirsten Block |
Ronald Breaker |
| Dissecting Kinase Signaling Pathways Using Protein Microarrays |
Joseph Fasolo |
Michael Snyder |
| Riboswitches as Antibiotic Drug Targets and the Characterization of
Newly Discovered Riboswitches |
Elaine Lee |
Ronald Breaker |
| Natural Variation of the Hydractinia symbiolongicarpus Allodeterminant
alr2
|
Rafael Rosengarten |
Stephan Dellaporta |
| |
|
|
| May 2010 |
|
|
| Bacterial Cell Curvature Through Mechanical Control of Cell Growth |
Matthew Cabeen |
Christine Jacobs-Wagner |
| MicroRNAs and Cancer: A Two Part Study in the Roles of microRNAs in Melanoma and in Oncogenic Virus
Infection |
Sirie Godshalk |
Frank Slack |
| Roles of the Arabidopsis COP10-DET1-DDB1 Complex in Plant Development |
On Sun Lau |
Xing-Wang Deng |
| Genomic Investigation of SREBP Family Transcription Factors Using ChIp-chip and ChIP-seq |
Brian Reed |
Michael Snyder & Sherman Weissman |
| Exploring the Sequence Sensitivity And Substrate Specificity of the Processive Viral Helicase NPH-II |
Sean Taylor |
Anna Pyle |
| |
|
|
| December 2009 |
|
|
| Analysis of the Spatio-temporal Distribution and Function of the Caulobacter crescentus Essential Histidine Kinase CckA |
Peter Angelastro |
Christine Jacobs-Wagner |
| Acj6, a Dual Regulator of Olfactory Receptor Genes |
Lei Bai |
John Carlson |
| Slit/Robo Signaling in Neuronal Morphogenesis |
Jennifer Round |
Elke Stein |
| The Molecular and Cellular Basis of Bitter Taste in Drosophila |
Linnea Weiss |
John Carlson |
| |
|
|
| May 2009 |
|
|
| Role for MKL1 in Megakaryocytic Maturation |
Ee-Chun Cheng |
Diane Krause |
A Study of microRNA Complementary Sites in the 3' UTRs of Lung Cancer-associated Oncogenes |
Lena Chin |
Frank Slack |
| Myo2 Regulation in S. pombe |
Janice Friend |
Thomas Pollard |
| Remodeling Miniature Proteins that Target EVH1 Domains with High Affinity and Specificity |
Jennifer Holtzman |
Alanna Schepartz |
| Spatial Organization of Gene Expression in Caulobacter crescentus |
Audrey Jackson |
Christine Jacobs-Wagner |
| Discovery and Applications of Purine-sensing Riboswitches |
Jane Kim |
Ronald Breaker |
| Functional Analysis of Agamous Clade Genes in Tomato |
Irvin Pan |
Vivian Irish |
| A Legionella pneumophila Dot/Icm Substrate Protein that Interferes with Vesicular Transport |
Xiaoxiao Pan |
Craig Roy |
| |
|
|
| December 2008 |
|
|
| Investigating the Role of tasselseed1 and silkless1 in the Sex Determination Process of Maize |
Ivan Acosta |
Stephen Dellaporta |
| Serine Proteases and Serpins Involved in Drosophila Immune Melanization |
Huaping Tang |
Carl Hashimoto |
| A Novel Drosophila POU Gene, pdm3, Acts in Olfactory Receptor Neuron Development |
Andrea Tichy |
John Carlson |
| |
|
|
| May 2008 |
|
|
| Chloroplastic Protein NRIP1 is Required for N Immune Receptor Recognition of Tobacco Mosaic Virus |
Jeffrey Caplan |
S.P. Dinesh-Kumar |
| Temporal Regulation of Neuronal Maturation in C. elegans |
Katherine Olsson Carter |
Frank Slack |
| Molecular Mechanisms Linking Inflammation, Cancer and Chemoresistance |
Rui Chen |
Gil Mor/Harold Behrman |
| Differential Delta Signaling During Zebrafish Somitogenesis and Midline Development |
Andrew Mara |
Scott Holley |
| Identification and Characterization of Targets of APETALA3 and PISTILLATA |
Chloe Diamond Mara |
Vivian Irish |
| Identification and Characterization of Riboswitches that Sense PreQ1 and Molybdenum Cofactor |
Elizabeth Regulski Meyer |
Ronald Breaker |
| Analysis of Mechanisms that Regulate Neurotransmitter Release from a Pair of Motor Neurons in Caenorhabditis elegans |
Jessica Tanis |
Michael Koelle |
| Identification of Regulators of Neuronal Differentiation by High Throughput Screening of Embryonic Stem Cells |
Elias Theodorou |
Michael Snyder |
| |
|
|
| December 2007 |
|
|
| Neuronal Growth Cone Actomyosin II Contractile Systems: Dynamic Barriers Controlling Microtubule Distribution and Function |
Dylan Burnette |
Paul Forscher |
| Unraveling Signaling Pathways Activated by VH1, an Arabidopsis Provascular/Procambial Specific Receptor-like Kinase |
Teresa Ceserani |
Timothy Nelson |
| The Role of CPEB1 Mediated and mRNA Translation in Astrocytes |
Kendrick Jones |
David Wells |
| Functional Characterization of the Mammalian COP9 Signalosome |
Suchithra Menon |
Xing-Wang Deng |
| Taste Coding in Drosophila |
Jennifer Perry |
John Carlson |
| Analysis of Aberrant and Normal Copy-Number Variation of Human Chromosome 22 |
Alexander Urban |
Michael Snyder
Sherman Weissman |
| |
|
|
| May 2007 |
|
|
| Pathway of Actin Filament Branch Formation by Arp2/3 Complex |
Christopher Beltzner |
Thomas Pollard |
| A Developmental Timing microRNA and its Target Regulate Lifespan in C. elegans |
Michelle Boehm |
Frank Slack |
| The Molecular Mechanisms of TRAPP Mediated Vesicle Tethering |
Huaqing Cai |
Susan Ferro-Novick |
| Genetic Variation and Linkage Disequilibrium in ADH Genes |
Yi Han |
Kenneth Kidd |
| The Molecular Basis of Olfaction in the Drosophila Larva |
Scott Kreher |
John Carlson |
| CPEB1-mediated mRNA Translation in Purkinje Neurons is Required for Cerebellar Long-term Depression and Motor Coordination |
Michael McEvoy |
David Wells |
| A ZIP1 Separation-of-Function Mutation Triggers Meiotic Arrest with Synapsed Chromosomes |
Neal Mitra |
Shirleen Roeder |
| Unraveling the Developmental Pathways of Cardiovascular Morphogenesis and the Pathogenic Mechanisms of Congenital Heart Defects Through Classical and Proteomic Approaches |
Anjali Nath |
Michael Snyder
Joseph Madri |
| The Regulation of Adipose Mass by DeltaFosB Isoforms |
Glenn Rowe |
Roland Baron |
| Autophagy-Dependent and –Independent Roles of ATG1 in the Coordination of Cell Differentiation, Cell Survival, and Cell Death |
Montrell Seay |
Savithramma Dinesh-Kumar |
| |
|
|
| December 2006 |
|
|
| The Role of the F-box Protein UFO in Regulation of the Floral Homeotic APETALA3 Gene |
Eunyoung Chae |
Vivian Irish |
| Functional Analyses of the B Class Genes in Tomato |
Gemma de Martino |
Vivian Irish |
| Genomic Landscapes and Hormone Action in Drosophila |
Zareen Gauhar |
Kevin White |
| Wrestling with Meiotic Chromosomes: A Role for Sumoylation in Meiotic Chromosome Synapsis |
Gillian Hooker |
Shirleen Roeder |
| Analysis of Transcriptome in Rice and Arabidopsis |
Yuling Jiao |
Xing-Wang Deng |
| Nuclear Localization of Met, the HGF Receptor, in Cell Signaling and Breast Cancer |
Sharon Moulis |
David Rimm |
| Spatiotemporal Regulation of Arabidopsis Petal and Stamen Differentiation |
Naomi Nakayam |
Vivian Irish |
| Post-embryonic Characterization of puf-9, a C. elegans Puf Family Protein |
Mona Nolde |
Frank Slack |
| Leaf Vascular Patterning Mutants in Arabidopsis thaliana: Making Connections |
Jalean Petricka |
Timothy Nelson |
| A Role for the Heterochronic Gene lin-41 During Vertebrate Development |
Betsy Schulman |
Frank Slack |
| |
|
|
| May 2006 |
|
|
| Mechanism of Action of ADF/cofilin Proteins |
Ernesto Adrianantoandro |
Thomas Pollard |
| The N Resistance Protein Recognizes its Tobacco Mosaic Virus Elicitor Through a Novel Mechanism |
Tessa Burch-Smith |
Savithramma Dinesh-Kumar |
| Studies on the Regulation of Normal Trophoblast Apoptosis and Survival During Pregnancy |
Shawn Chavez |
Harold Behrman
Gil Mor |
| Statistical Modeling of Transcription Regulation in Eukaryotes |
Liang Cheng |
Hongyu Zhao |
| Identification of Yeast Kinase Substrates Using Proteome Arrays |
Geeta Devgan |
Michael Snyder |
| Regulation of SCF-type E3 Ubiquitin Ligases by the COP9 Signalosome and CAND1 |
Suhua Feng |
Xing-Wang Deng |
| Global Analyses of STAT Target Selection and Transcription Regulation |
Stephen Hartman |
Michael Snyder |
| Regulation of Polarity and Cell Cycle Progression in Caulobacter Crescentus |
Hubert Lam |
Christine Jacobs-Wagner |
| Characterization of Meiosis-Specific Mer2 in Double-Strand Break Formation and Ssp2 and Ssp3 in Spore Morphogenesis |
Jing Li |
Shirleen Roeder |
| Cloning of RCY1 and Characterization of its Role in Cucumber Mosaic Virus Resistance in Arabidopsis Thaliana |
Jennifer Soosaar |
Savithramma Dinesh-Kumar |
| Mechanisms of Chromosome Synapsis and Crossover Distribution During Meiosis in S. cerevisiae |
Tomomi Tsubouchi |
Shirleen Roeder |
| |
|
|
| December 2005 |
|
|
| Deletion Mutations Caused by DNA Strand Slippage in Acinetobacter baylyi |
Jeremy M. Gore |
L. Nicholas Ornston |
| Conserved Molecules and Mechanisms of Neuronal Signaling Revealed by the Analysis of Simple Nematode Behaviors |
Antony M. Jose |
Michael Koelle |
| |
|
|
| May 2005 |
|
|
| Microarray Approaches to Experimental Genome Annotation |
Paul N. Bertone |
Michael Snyder/Mark Gerstein |
| Control of Immunity by Toll-like Receptors and Semaphorins |
Agnieszka K. Czopik |
Ruslan Medzhitov |
| Functional and Biochemical Characterization of Sec15p, a Subunit of the Exocyst Complex |
Yen Kang Ellen France |
Peter Novick |
| Odor Receptor Gene Choice in Drosophila |
Anandasankar Ray |
John Carlson |
| Characterization of the Mammalian Homologue of an Arabidopsis Developmental Switch Protein – COP1 |
Chunling Yi |
Xing-Wang Deng |
| |
|
|
| December 2004 |
|
|
| Vascular Patterning and Leaf Development in Arabidopsis |
Nicole Kho Clay |
Vivian Irish |
| The Molecular Basis of Odor Coding in the Drosophila Maxillary Palp |
Aaron L. Goldman |
John Carlson |
| Identification of Nuclear Factor-KappaB Binding Sites on Chromosome 22 |
Rebecca B. Martone |
Michael Snyder |
| The Role of Mouse Numb and Numblike During Mammalian Development and Neurogenesis |
Petur H. Petersen |
Weimin Zhong |
| In vivo Validation and Architecture of a microRNA::Target Interaction in C. elegans |
Monica C. Vella |
Frank Slack |
| |
|
|
| May 2004 |
|
|
| The Ig Protein Turtle is a Genetic Inhibitor of the EGFR Pathway that Functions in Axonal Guidance and Rhabdomere Morphology in Drosophila melanogaster |
Badar F. Al-Anzi |
Robert Wyman |
| Unconventional Myosin Function in the Immune System |
Jeffrey P. Holt |
Mark Mooseker |
| Regulation and Role of C. elegans let-7 Family of MicroRNAs |
Steven M. Johnson |
Frank Slack |
| |
|
|
| December 2003 |
|
|
| Cytoskeletal Activation of a Checkpoint Kinase: Delineation of the Functional Domains of Hsl1 |
Jessie Hanrahan |
Michael Snyder |
| Extragenic Suppressor of Growth Defects in msbB Salmonella |
Sean R. Murray |
Brooks Low |
| Isolation and Characterization of the Homeodomain Protein 137, a Putative Regulator of APETALA3 |
Khoon Ghee QueenieTan |
Vivian Irish |
| |
|
|
| May 2003 |
|
|
| Gene Expression Analysis of ErbB2 Family Signaling: Encodement of Signaling Specificity and Identification of Targets of ErbB2 and ErbB4 |
Dhara N. Amin |
David Stern |
| Analysis of the Mechanisms of Ventral Body Wall and Heart Outflow Tract Development in Wild-Type and AP-2 a Mutant Mice |
Stephanie L. Brewer |
Trevor Williams |
| Molecular Genetics of Odor Reception and Development in Drosophila |
Anna A. Dobritsa |
John Carlson |
| Selection and Analysis of RNA-Cleaving Deoxyribozymes and Ribozymes: Application Toward Understanding Enzyme Structure and Function |
Gail A. Emilsson |
Ronald Breaker |
| Coordination of Two Checkpoint Pathways Couples Recombination and Cell Cycle Progression During Meiosis in Yeast |
Eun-Jin Hong |
Shirleen Roeder |
| A Novel Approach for Transcription Factor Target Identification: Studies of the Saccharomyces cerevisiae Cell Cycle and the Human b-globin Locus |
Christine E. Horak |
Michael Snyder |
| Functional Analysis of a Regulatory Element Controlling Spatial and Temporal Expression of Hoxc-8 in Mouse Development |
Hsin Juan |
Frank Ruddle |
| AP-2 a is Required for Embryonic and Postnatal Craniofacial Development |
Danielle K. Nelson |
Trevor Williams |
| Biological Insights into Intraepithelial Lymphocytes Provided by Serial Analysis of Gene Expression |
John C. Shires |
Adrian Hayday |
| |
|
|
| December 2002 |
|
|
| Expansion of an “Island of Catabolic Diversity”: Genetic Analysis of Hydroxycinnamate Catabolism in Acinetobacter sp. Strain ADP1 |
Michael A. Smith |
L. Nicholas Ornston |
| |
|
|
| May 2002 |
|
|
| Transcription Factor AP-2 g: Genetic Insight into Placental Development |
Heidi J. Auman |
Trevor Williams |
| Studies on Developmental Transitions During Drosophila Oogenesis |
Michael H. Buszczak |
Lynn Cooley
William Segraves |
| Mode of Action Study of the Anti-inflammatory Sesquiterpene Lactone Partheonolide |
Benjamin H.B. Kwok |
Craig Crews |
| Mechanistic Understanding of Nucleoside Inhibitors of Human Immunodeficiency Virus |
Adrian S. Ray |
Karen Anderson |
| Molecular and functional Analysis of the COP9 Signalsome in Arabidopsis |
Giovanna Serino |
Xing-Wang Deng |
| Biological and Genetic Characterization of a Naturally Transformable Acinetobacter strain |
David M. Young |
L. Nicholas Ornston |
| Mutagenesis Induced by the Tumor Microenvironment – Implications of Increased DNA Damage and Diminished DNA Repair |
Jianling Yuan
(MD/PhD) |
Peter Glazer |
| |
|
|
| December 2001 |
|
|
| Requirements for the c-Myc Proto-Oncogene in Physiologic T Cell Development |
Nataki C. Douglas
(MD/PhD) |
Alfred Bothwell
Adrian Hayday |
| The Role of the Ecdysone Early-Response Gene E75 in Drosophila Development |
Alycia N. Shilton |
William Segraves |
| Cloning and Characterization of Drosophila Filamin |
Nicholas S. Sokol |
Lynn Cooley |
| A Study of Anti-Angiogenic Agent TNP-470: Revealing a Unique Mechanism of Endothelial Cell Cycle Control and Genetic Targeting of Methionine Aminopeptidase-2, the Binding Protein of TNP-470 |
Jing-Ruey Joanna Yeh |
Craig Crews |
| |
|
|
| May 2001 |
|
|
| The Role of Regulator of G-protein Signaling (RGS9) Proteins in Drug Addiction |
Zia Ur Rahman |
Eric Nestler |
| |
|
|
| |
|
|
| December 2000 |
|
|
| Analysis of the Cis-Regulatory System of the Arabidopsis Floral Homeotic Gene APETALA3 |
Theresa A. Hill |
Vivian Irish |
| Clonal and Mosaic Analyses of the Floral Homeotic Gene APETELA3 in Arabidopsis |
Pablo D. Jenik |
Vivian Irish |
| Studies on the Regulation of Final Cytoplasm Transport During Oocyte Development in Drosophila melanogaster |
Nina M. Matova |
Lynn Cooley |
| Eponemycin and Epoxomicin as Probes of the 20S Proteasome Function |
Lihao Meng |
Craig Crews |
| |
|
|
[Top]
|
|
|
