Biological
& Biomedical Sciences
Ph.D.
http://info.med.yale.edu/bbs
Fields of Study The Graduate School and the School of Medicine
offer a combined interdepartmental program in the Biological and
Biomedical Sciences (BBS) that provides students opportunities to
study and conduct research with more than 280 biological science
faculty at the School of Medicine and Science Hill campuses. BBS
also offers firsthand experience in pharmaceutical research through
an
alliance with Bristol-Myers Squibb in nearby Wallingford. BBS consists
of eight interest-based tracks: Computational Biology and Bioinformatics;
Immunology; Microbiology; Molecular Biophysics & Biochemistry;
Molecular Cell Biology, Genetics & Development; Neuroscience;
Pharmacological Sciences & Molecular Medicine; and Physiology
& Integrative Medical Biology.
Profile For information from the Graduate School
Bulletin regarding faculty, degree requirements, course offerings,
and combined and joint degree programs, please click here.
For a profile of this and other programs at the Graduate School,
including admissions data, total enrollment, time to degree, and
career data, please click here.
Special Admissions Requirements Relevant GRE Subject Test
recommended. In special cases, MCAT scores may be substituted for
GRE General Test scores for the Immunology track. Students who are
required to take the TOEFL must score a minimum of 600 on the paper-based,
or 250 on the computer-based version.
Applying to BBS There is one method available for applying
to the BBS program, the online
application of the Graduate School of Arts and Sciences. Students
applying to BBS should state on their application the one or two
tracks that best represent their interests; applications will be
evaluated by that track (or tracks). Affiliation does not limit
a student’s opportunities to work with faculty or participate
in training activities of the other tracks. At the end of the first
year, a student selects an adviser and a department or program in
which to take the qualifying examination (in the second year) and
through which he or she will be awarded a Ph.D. degree.
Computational
Biology & Bioinformatics
This track provides a broad interdisciplinary program at the interface
of Biology, Computer Science, Statistics, and Mathematics. Emphasis
is placed on large-scale biological research including genomics,
proteomics, and comparative biology. Research and training involve
four core areas: bioinformatics and computational biology, biological
sciences, computer sciences, and biostatistics and mathematics.
Students are exposed to biological data modeling, structural biology,
comparative biology, statistical genomics, and theoretical biology.
Immunology
Track
This track focuses on the molecular, cellular, and genetic underpinnings
of immune system function and development, and on host-pathogen
interactions. Research areas include T-cell development, activation
and effector functions, the role of cytokines in immunoregulation,
intracellular signaling and the control of transcription in lymphocytes,
antigen processing and presentation, immunoglobulin and T-cell receptor
gene rearrangement, immunological memory, the immunobiology of vascular
endothelial cells, and B-and T-cell tolerance. |
Microbiology
Track
Training and research utilize cellular, molecular, and genetic approaches
in the study of microorganisms and their effects on their hosts.
Specializations include bacteriology, virology, microbe-host interactions,
vector biology, microbial pathogenesis and parasitology, microbial
genetics, ecology, evolution, and physiology.
Molecular
Biophysics & Biochemistry Track
MB&B is designed to prepare students for careers as independent
investigators in molecular and structural biology. Faculty come
from the departments of Molecular Biophysics and Biochemistry; Molecular,
Cellular, and Developmental Biology; Chemistry; and Genetics. Research
is being pursued in control of the cell cycle and animal development;
structure and function of proteins and nucleic acids; catalytic
rna’s and rna processing; signal transduction in plants and
mammals; protein folding; cell motility; molecular immunology; and
more.
Molecular
Cell Biology, Genetics & Development
Molecular cell biology and genetics have emerged as central to virtually
all pursuits in the biological and biomedical sciences. Research
opportunities include genetic and functional analysis in yeast,
Drosophila, C. elegans, and mammalian cells and tissues. Highly
specialized experimental approaches include high-resolution confocal
microscopy and image analysis, electron microscopy and immunocytochemistry,
functional genomics, and the fluorescence imaging of living cells.
Neuroscience
Track
This track offers training and research in virtually all areas of
neurobiology, from the mathematical to the molecular to the integrative,
in virtually all experimental systems ranging from C. elegans to
Drosophila to mammals.
Pharmacological
Sciences & Molecular Medicine Track
This track offers the opportunity to use tools from genetics, immunology,
cell, and molecular biology to investigate the mechanisms of disease
pathogenesis and apply the findings to diagnosis and treatment.
Specific areas of investigation include cancer and viral diseases,
atherosclerosis, inflammation and wound healing, neurophysiology,
pyschopharmacology, disorders of coagulation, and immune and genetic
disorders.
Physiology
& Integrative Medical Biology
This track includes cell systems and integrative physiology. Research
integrates information from genetics, functional genomics, and functional
proteomics into whole animal and human biology, including pathophysiology,
pharmacology, translational research, and biomedical engineering.
Areas of current interest include ion channels, solute transporters
and pumps, membrane biophysics, electrophysiology, epithelial transport,
cellular and systems neurobiology, structural biology of membrane
proteins, physiological genomics, signal transduction pathways,
vascular biology, organ physiology, small animal physiology, genetic
models of human disease, pathophysiology, and more.
Administrative Office
John Alvaro
bbs@yale.edu
(203) 785-3735
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