RNA-Biochemist: Post-doctoral positions

RNA Biochemist

Research Area: RNA biochemistry, RNA protein interactions, iClip, Mass spectrometry

Project title: Identification of the protein-RNA interactions that mediate post-transcriptional regulation in development

Description of project:  A postdoctoral position is available to identify and characterize RNA-protein interactions that regulate mRNA decay and translational regulation during vertebrate development

Applicants require a strong background RNA and protein biochemistry

Please e-mail CV, summary and relevance of your current research (500 word max), why you are interested in the giraldez lab (200 word max) and names of three references to: giraldezlab@gmail.com
Please include the title “RNA biochemistry, Postdoctoral Position 2012” in the subject of the e-mail

These are some of the papers recently published by the laboratory:

  1. 1.Moreno-Mateos MA, Vejnar CE, Beaudoin JD, Fernandez JP, Mis EK, Khokha MK and Giraldez AJ‡. CRISPRscan: designing highly efficient sgRNAs for CRISPR/Cas9 targeting in vivo. Nature Methods. 2015.

  2. 2.Bazzini AA, Johnstone TG, Christiano R, Mackowiak SD, Obermayer B, Fleming ES, Vejnar CE, Lee MT, Rajewsky N, Walther TC, Giraldez AJ. Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation.EMBO J. 2014 May 2;33(9):981-93.

  3. 3.Lee MT*, Bonneau AR*, Takacs CM, Bazzini AA, Divito KR, Fleming ES, Giraldez AJ Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition. Nature. 2013 Sep 22. 

  4. 4.Bazzini AA, Lee MT, Giraldez AJ‡. Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish. Science 13 April 2012: 233-237.

  5. 5.Cifuentes D, Xue H, Taylor DW, Patnode H, Mishima Y, Cheloufi S, Ma E, Mane S, Hannon GJ, Lawson N, Wolfe S, Giraldez AJ‡. A novel miRNA processing pathway independent of Dicer requires Argonaute2. Science. 2010, Jun 25

  6. 6.Giraldez AJ‡, Mishima Y, Rihel J, Grocock R, van Dongen S, Inoue, K, Enright A, and Schier AF‡. Zebrafish miR-430 promotes deadenylation and clearance of maternal mRNAs. Science. 2006 Apr 7

Thanks for checking out our postings for positions:

We are a lab of scientists who are passionate about what we do, with interests and expertise spanning Development, Biochemistry, Genomics, and Computational biology. Our projects are focused on collaborative, integrative science to study the earliest steps of vertebrate development. We are looking for scientists who share our passion for science and would like to work in a friendly, multidisciplinary and multicultural environment.