Giraldez Lab Papers

Zygotic genome activation during the maternal-to-zygotic transition.

Lee MT, Bonneau AR, Giraldez AJ.

Annu Rev Cell Dev Biol. 2014;30:581-613. doi: 10.1146/annurev-cellbio-100913-013027. Epub 2014 Aug 11. [PDF]

Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation.

Bazzini AA, Johnstone TG, Christiano R, Mackowiak SD, Obermayer B, Fleming ES, Vejnar CE, Lee MT, Rajewsky N, Walther TC, Giraldez AJ.

EMBO J. 2014 May 2;33(9):981-93. doi: 10.1002/embj.201488411. Epub 2014 Apr 4. [PDF]

Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition.

Lee MT*, Bonneau AR*, Takacs CM, Bazzini AA, Divito KR, Fleming ES, Giraldez AJ

Nature. 2013 Sep 22. doi: 10.1038/nature12632. [PDF]

PARN mediates 3′-end trimming of Argonaute-cleaved precursor microRNAs

Yoda M #, Cifuentes D #, Izumi N, Sakaguchi Y, Suzuki T, Giraldez AJ‡ and Tomari Y‡.

Cell Reports, Nov 14;5(3):715-26. doi: 10.1016/j.celrep.2013.09.029. Epub 2013 Oct 24.  [PDF]

miR-1 and miR-206 regulate angiogenesis by modulating VegfA expression in zebrafish.

Stahlhut C, Suárez Y, Lu J, Mishima Y, Giraldez AJ.

Development. 2012 Dec 1;139(23):4356-64. [PDF][Supp Material]

Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish.

Bazzini AA, Lee MT, Giraldez AJ. Science. 13 April 2012: 233-237. [PDF][Supp Material]

Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo

Alison A Staton & Antonio J Giraldez.2011. 423 Nature Protocols. December 2011, Volume 6 No 12 - pp2035 - 2049 [PDF]

miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration

Staton AA, Knaut H and Giraldez AJ. Nature Genetics. 2011. Published online 23 January 2011. [PDF]

MicroRNAs Sculpt Gene Expression in Embryonic Development: New Insights from Plants.

Bazzini AA, Giraldez AJ. Dev Cell. 2011 Jan 18;20(1):3-4. [PDF]

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).

Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, Dobbs D, Langenau DM, Stupar RM, Giraldez AJ, Voytas DF, Peterson RT, Yeh JR, Joung JK. Nat Methods. 2010 Dec 12. [PDF]

A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity.

Cifuentes D, Xue H, Taylor DW, Patnode H, Mishima Y, Cheloufi S, Ma E, Mane S, Hannon GJ, Lawson ND, Wolfe SA, Giraldez AJ. Science. 2010 Jun 25;328(5986):1694-8. Epub 2010 May 6. [PDF] [Supp_Material]

microRNAs, the cell's Nepenthe: clearing the past during the maternal-to-zygotic transition and cellular reprogramming.

Giraldez AJ. Curr Opin Genet Dev. 2010 Aug;20(4):369-75. Epub 2010 May 6. Review. [PDF]

MicroRNAs as genetic sculptors: fishing for clues.

Takacs CM, Giraldez AJ. Semin Cell Dev Biol. 2010 Sep;21(7):760-7. Epub 2010 Feb 10. Review. [PDF]

Zebrafish miR-1 and miR-133 shape muscle gene expression and regulate sarcomeric actin organization.

Mishima Y, Abreu-Goodger C, Staton AA, Stahlhut C, Shou C, Cheng C, Gerstein M, Enright AJ, Giraldez AJ.  Genes & Development. 2009 Mar 1;23(5):619-32. (Cover) [PDF] [Supp Material] [Supp Material 2]

MicroRNAs in Development and Disease

Alison A Staton, Antonio J Giraldez. Encyclopedia of Life Sciences. ELS. Review. Published online: 15 July, 2008 [PDF]

Members of the miRNA-200 Family Regulate Olfactory Neurogenesis.

Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C. Neuron. 2008 Jan 10;57(1):41-55. [PDF]

Target Protectors Reveal Dampening and Balancing of Nodal Agonist and Antagonist by miR-430.

Choi WY, Giraldez AJ‡, Schier AF‡.  Science. 2007 Oct 12;318(5848):271-4. ‡Corresponding authors.[PDF] [Supp Material]

miR-1-2 gets to the heart of the matter.

Mishima Y, Stahlhut C, Giraldez AJ‡.  Cell. 2007 Apr 20;129(2):247-9. Review. [PDF]

MicroRNA function and mechanism: insights from zebra fish.

Schier AF, Giraldez AJ.  Cold Spring Harb Symp Quant Biol. 2006. 71:195-203. Review.[PDF]

Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430.

Mishima Y#, Giraldez AJ#, Takeda Y, Fujiwara, T, Sakamoto H, Schier AF, Inoue K.  (2006)  Curr Biol, 2006. Nov 7;16(21):2135-42 [PDF]

Zebrafish miR-430 promotes deadenylation and clearance of maternal mRNAs.

Giraldez AJ‡, Mishima Y, Rihel J, Grocock R, van Dongen S, Inoue, K, Enright A, and Schier AF‡.  Science. 2006.Apr 7;312(5770):75-9. ‡Corresponding authors.[PDF] [Supp Material]

MicroRNAs regulate brain morphogenesis in zebrafish.

Giraldez AJ‡, Cinalli RM, Glasner ME, Enright A, Thomson JM, Baskerville S, Hammond SM, Bartel D, and Schier AF‡.  Science. 2005 May 6;308(5723):833-8. ‡Corresponding authors. [PDF] [Supp Material]

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Giraldezlab papers from pubmed

eLIFE    Nature    Science    Cell    Developmental Cell    G&D    Nature Genetics   

Development    RNA Molecular Cell   EMBO J  microRNAs    zebrafish   

lncRNAs    MZT  Faculty 1000    DB   DMB   MB    GG