Table 1. Summary of the COP/DET/FUS loci and their respective molecular identities.
|
COP/DET/FUS locus name
|
Other protein names
|
Function
|
|
COP1
|
Putative ubiquitin ligase component;
promotes HY5 & HYH degradation(a)
|
|
|
DET1
|
Nuclear protein required for HY5 &
HYH degradation(b),
|
|
|
COP10
|
E2 variant(c)
|
|
|
COP16
|
Not cloned(d)
|
|
|
COP11
|
CSN1
|
COP9 signalosome subunit 1(e)
|
|
FUS12
|
CSN2
|
COP9 signalosome subunit 2(f)
|
|
FUS11
|
CSN3
|
COP9 signalosome subunit 3(g)
|
|
COP8
|
CSN4
|
COP9 signalosome subunit 4(h)
|
|
FUS5
|
CSN7
|
COP9 signalosome subunit 7(i)
|
|
COP9
|
CSN8
|
COP9 signalosome subunit 8(k)
|
Table 2. CSN subunit composition and identity in Arabidopsis and human.
|
Subunit
|
MW (kDa) Arabidopsis
|
Motif
|
Other names Arabidopsis
|
Other names mammals
|
Identity (%) with human
|
|
CSN1
|
50
|
PCI
|
COP11/FUS6(a)
|
GPS1(i)
|
44.7
|
|
CSN2
|
51
|
PCI
|
FUS12/COP12(b)
|
TRIP15(l),
ALIEN
|
61.1
|
|
CSN3
|
47
|
PCI
|
FUS11/COP13(c)
|
42.0
|
|
|
CSN4
|
45
|
PCI
|
COP8/FUS4(d)
|
49.5
|
|
|
CSN5
|
40
|
MPN
|
AJH1(e),
AJH2
|
JAB1(m)
|
62.0
|
|
CSN6
|
35
|
MPN
|
CSN6a(f),
CSN6b
|
HVIP(n)
|
39.8
|
|
CSN7
|
25
|
PCI
|
FUS5/COP15(g)
|
34.4
|
|
|
CSN8
|
22
|
PCI
|
COP9/FUS7/FUS8(h)
|
32.3
|