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The broad foci of the Crews Laboratory are:

1) The application of chemical approaches to the study of biological questions. Current projects explore the modes of action of biologically active natural products in order to investigate intracellular signaling pathways and identify novel targets for drug design.

2) The investigation of the molecular mechanisms of cell dedifferentiation and wound healing in regenerating limbs. Current projects focus on the development of in vitro models of urodele limb regeneration.

 

Research

» Natural product total synthesis

» Mode of action studies

» Small molecule control of protein function

» Cell dedifferentiation & tissue regeneration

News

» Lab news

» Lab photo gallery

Positions open

» Cell Biologist

» Limb Regeneration/Wound Healing

 

Craig M. Crews

Professor of Molecular, Cellular, and Developmental Biology

Professor of Chemistry

Professor of Pharmacology

B.A., Chemistry, University of Virginia, 1986; DAAD Fellow, University Tübingen, 1986-87; Ph.D., Biochemistry, Harvard University, 1993

Cancer Research Institute Postdoctoral Fellow, Chemistry and Chemical Biology, Harvard University 1993-1995; joined Yale Faculty 1995

 

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Updated January 27, 2008 [tn]