Departments M - Z
Molecular Biophysics and Biochemistry
Offices: JWG 304, 432.2077; SHM C106, 785.4246
Professors
D. M. Crothers (Chemistry), J. Doudna, D. M. Engelman, J. Fruton (Emeritus),
A. Garen, S. Ghosh (Immunobiology), N. D. F. Grindley (Director of Graduate
Studies), A. Hamilton (Chemistry), M. Hochstrasser, W. H. Konigsberg, P. Lengyel
(Emeritus), R. Lifton (Genetics), R. M. Macnab, I. G. Miller (Pediatrics), S.
G. J. Mochrie (Physics), , P. B. Moore (Chemistry), C. M. Radding (Genetics),
L. Regan, F. M. Richards (Emeritus), G. L. Schmir (Emeritus), R. G. Shulman,
S. Simmonds (Emeritus), O. Sinanoglu (Emeritus), M. Snyder (Molecular, Cellular,
and Developmental Biology), D. Söll, J. A. Steitz, T. A. Steitz (Chair),
S. Strobel (Director of Undergraduate Studies), J. M. Sturtevant (Emeritus),
W. C. Summers (Therapeutic Radiology), D. C. Ward (Genetics), H. W. Wyckoff
(Emeritus)
Professor of Research
K. Williams (Adjunct)
Associate Professors
M. Gerstein (Director of Graduate Admissions), M. Koelle, M. Solomon, S. Wolin
Assistant Professors
J. Cabral, E. De La Cruz, L. Heginbotham, A. Koleske (Director of Medical Studies),
A. Miranker, V. Unger
Senior Research Scientists
C. Joyce, P. Lengyel, F. M. Richards, H. Wyckoff
Research Scientists
K. Tycowski, J. Wang
Visiting Research Scientists/Scholars
M. Locher, J. Wen
Associate Research Scientists
A. Amerik, S. Balasubramanian, M. Cocco, J. Countryman, J. Elliott, E. Folta-Stogniew,
E. J. Hager, K. Hager, Z. Hu, Z. S. Juo, S. Kamtekar, W. Kennedy, S.-J. Li,
T. McConnell, J. Pata, T. Pauly, G. Sarkis, A. J. Scheetz, D. Tumbula
Postdoctoral Fellows
C. Bevans III, G. Blaha, J. Burton, D. Chase, A. Cheng, H. S. Choi, A. R. Curran,
A. Eversole, G. Fraser, Y. Fujii, I. Gallouzi, I. Ghosh, J. Hansen, T. Hirose,
Y. Huang, S. Jaswal, W. D. Kennedy, J. Lykke-Andersen, E. Main, T. Marlovits,
G. Muth, A. Oyelere, M. Ramirez-Alvarado, A. Rebane, Y. Wang, L. Weinstein,
Z. Zhang
Postdoctoral Associates
P. Adams, L. Aramli, C. Becker, H. Becker, P.-J. Chang, L. Chen, B. Ding, L.
Feng, B. Gonzalez-Pedrajo, P. Harrison, J. Junker, T. Kawashima, J. Kieft, D.
Klimenko, Y. Kluger, N. Lan, J. Laney, G. Li, J. Li, J. Li, Y. Liu, D. Luisi,
N. Luscombe, B. Min, K. Mitra, J. Murray, N. Nakano, S. Namgoong, D. Ostapenko,
A. Patel, V. Purohit, J. Qian, B. Ruan, W. Russ, M. B. Sagar, T. Serio, X. Song,
C. Stathopoulos, Y. Sun, A. Szewczak, H. Toogood, I. Ubarretxena, I. Velichutina,
C.-X. Wang, G. Yang, W. Yin, W. Zhao, K. Zhu
Postgraduate Associates
I. Ahel, A. Ambrogelly, T. Hirano, B. Knapp, D. Korencõi´c, R.
C. Polycarpo, G. Rosas-Sandoval, M. Sacher, J. Wall
Research Affiliate
W. Summers
Lecturers
A. Belperron, L. Denson (Pediatrics), O. Eickelberg, J. Kahn, N. Maun, J. McKinney,
A. Pawashe, V. Samuel, R. Sleight
Molecular Biophysics and Biochemistry 550a, Molecular Foundations of Medicine.
This course is part of the Molecules to Systems course, which is open only to
first-year medical students. An introduction to the major concepts of biochemistry
and molecular biology, with emphasis on the human body. Special attention is
devoted to how recent advances in basic science contribute to our understanding
and treatment of human disease. A. Koleske, M. Solomon, I. G. Miller. Conference
leaders: A. Belperron, L. Denson, O. Eickelberg, J. Kahn, N. Maun, J. McKinney,
V. Samuel.
Molecular Biophysics and Biochemistry 600a, Principles of Biochemistry I.
A rigorous introduction to the major concepts of biochemistry and to the process
of discovery in this discipline, with emphasis on macromolecular conformation,
physical processes in biochemistry, and carbohydrate, lipid, and amino acid
metabolism. M. Koelle, D. Engelman.
Molecular Biophysics and Biochemistry 601b, Principles of Biochemistry II.
The chemistry and metabolism of nucleic acids, the mechanism and regulation
of protein and nucleic acid synthesis, and selected topics in macromolecular
biochemistry. S. Strobel, J. Steitz.
Molecular Biophysics and Biochemistry 602a/Cell Biology 602a, Molecular
Cell Biology. Comprehensive introduction to the molecular and mechanistic
aspects of cell biology. Emphasizes fundamental issues of cellular organization,
regulation, biogenesis, and function at the single-cell level. Topics include
nuclear structure and nuclear- cytoplasm interactions, protein synthesis, membrane
biogenesis, secretion, endocytosis, receptor function, polarity and biological
symmetry, cytoskeleton, and the cell cycle. Emphasis on the development of experimental
strategies including genetics, molecular biology, immunocytochemistry, and in
vitro reconstitution. S. Wolin, G. Warren, T. Pollard, V. Unger.
Molecular Biophysics and Biochemistry 625a/Genetics 625a/MCDB 625a, Basic
Concepts of Genetic Analysis. The universal principles of genetic analysis
in eukaryotes are discussed in lectures. Students also read a small selection
of primary papers illustrating the very best of genetic analysis and dissect
them in detail in the discussion sections. While other Yale graduate molecular
genetics courses emphasize molecular biology, this course focuses on the concepts
and logic underlying modern genetic analysis. A brief review of undergraduate
genetics is offered in two optional lectures at the beginning of the term. Prerequisites:
undergraduate genetics and molecular biology courses or equivalents. T. Xu,
M. Koelle, G. S. Roeder, M. Stern.
Molecular Biophysics and Biochemistry 642a/Genetics 642a/MBIO 642a/ MCDB
642a, Roles of Microorganisms in the Living World. A topical course exploring
the biology of organisms. Emphasis is placed upon mechanisms underlying microbial
adaptations and how they influence biological systems. Prerequisites: biology,
chemistry, and biochemistry. N. Ornston, C. McMahon-Pratt, R. M. Macnab.
Molecular Biophysics and Biochemistry 650a and 651b, Laboratory Rotation
for First-Year Students. Three consecutive research laboratory experiences
lasting eight to ten weeks each. Required for all first-year graduate students.
N. D. F. Grindley.
Molecular Biophysics and Biochemistry 658a/Chemistry 558a, Research Topics
in Biophysics. An advanced treatment of the fundamental physical properties
that dictate the behavior of biological molecules. Taught with participation
of a number of biophysics faculty; extends to their current research specialties.
D. Crothers.
Molecular Biophysics and Biochemistry 660Lb, Laboratory for Biochemistry
and Biophysics. An intensive introduction to the principles and applications
of experimental techniques currently used in biochemistry, biophysics, and molecular
biology. A. Garen, A. Pawashe.
Molecular Biophysics and Biochemistry 675, Seminar for First-Year Students.
Required for all first-year graduate students. M. Koelle, A. Miranker, and staff.
Molecular Biophysics and Biochemistry 676b, Responsible Conduct of Research.
This course is designed for students who are beginning to do scientific research.
The course seeks to describe some of the basic features of life in contemporary
research and some of the personal and professional issues that researchers encounter
in their work. The course is run in a seminar/discussion format, and consists
of approximately six sessions during the spring term. First-year graduate students
are required to attend. L. Regan and staff.
Molecular Biophysics and Biochemistry 700b, Properties of Macromolecules.
Solution properties of macromolecules and current topics in biophysics, including
electrostatics, hydrodynamics, enzyme kinetics, molecular dynamics, and multiple
equilibria. Prerequisites: physical chemistry and biochemistry. L. Regan, M.
Gerstein, V. Unger.
Molecular Biophysics and Biochemistry 701b3, Diffraction Methods. Biological
applications of X-ray crystallography, small-angle X-ray, neutron scattering,
and cryoelectron microscopy. J. Cabral, J. Doudna, V. Unger.
Molecular Biophysics and Biochemistry 701b4, NMR Methods. Basic principles
of NMR with emphasis on biological applications in the primary literature. Application
areas include structure determination, drug binding, molecular recognition,
protein folding, and in vivo metabolism. Prerequisites: physical chemistry and
biochemistry. A. Miranker.
Molecular Biophysics and Biochemistry 705a/Genetics 705a/MCDB 505a, Molecular
Genetics of Prokaryotes. Molecular aspects of the storage, replication,
evolution, and expression of genetic material in prokaryotes. Prerequisites:
previous or concurrent introductory courses in genetics and biochemistry. N.
D. F. Grindley, C. Radding, J. Sweasy.
Molecular Biophysics and Biochemistry 710b4/C&MP 710b4, Electron Cryo-Microscopy:
A Versatile Tool for Studying the Structure of Biological Macromolecules and
Their Supramolecular Assemblies. Understanding cellular function requires
structural and biochemical studies at an ever-increasing level of complexity.
The course is an introduction into the concepts and applications of high-resolution
electron cryo-microscopy. This rapidly emerging, new technique is the only tool
known to date that allows biological macromolecules to be studied at all levels
of resolution ranging from their cellular organization to near atomic detail.
No specific prerequisites. However, parts of the course deal with diffraction
theory and physical principles of image formation. Therefore, knowledge of calculus
and basic physics is advantageous. V. Unger, F. Sigworth.
Molecular Biophysics and Biochemistry 741a, Structure and Chemistry of Proteins
and Nucleic Acids. Selected topics in the structure of proteins and nucleic
acids; sequence-dependent interactions between proteins and nucleic acids; chemical
modifications of DNA; chemical studies of DNA-binding proteins; catalytic RNA.
Prerequisite: biochemistry. J. Doudna, T. Steitz.
Molecular Biophysics and Biochemistry 743b/Genetics 743b, Molecular Genetics
of Eukaryotes. Selected topics in regulation of gene expression, genome
structure and evolution, signal transduction, and cellular physiology, development,
and carcinogenesis. Prerequisite: biochemistry or permission of the instructor.
M. Hochstrasser, A. Koleske.
Molecular Biophysics and Biochemistry 749a/Genetics 749a, Medical Impact
of Basic Science. Consideration of examples of recent discoveries in basic
science that have elucidated the molecular origins of disease or that have suggested
new therapies for disease. Emphasis is placed on the fundamental principles
on which these advances rely. Reading is from the primary scientific and medical
literature, with emphasis on developing the ability to read this literature
critically. Aimed at seniors and first-year graduate students. Prerequisite:
MB&B 600a/601b or the equivalent or permission of the instructor. J. Steitz,
M. Hochstrasser, A. Miranker, and staff.
Molecular Biophysics and Biochemistry 750a2, Biological Membranes. Biological
membranes and their resident proteins are essential for cellular function; yet
comparatively little is known about their structure and dynamics. This module
serves as a brief introduction to the biochemistry and biophysics of lipids,
lipid bilayers, and lipid-derived second messengers. In addition, structural
as well as functional aspects of the different classes of membrane proteins
are discussed along with an outline of experimental approaches used to achieve
an understanding of membrane protein structure and function at a molecular level.
V. Unger, L. Heginbotham, J. Cabral, D. Engelman.
Molecular Biophysics and Biochemistry 752a/MCDB 752a, Genomics and Bioinformatics.
Genomics describes the determination of the nucleotide sequence and many further
analyses to discover functional and structural information on all the genes
of an organism. Topics include the methods and results of functional and structural
gene analysis on a genome-wide scale as well as a discussion of the implications
of this research. Bioinformatics describes the computational analysis of genomes
and macromolecular structures on a large scale. Topics include sequence alignment,
biological database design, comparative genomics, geometric analysis of protein
structure, and macromolecular simulation. Prerequisites: EEB 112b and Math 115,
or permission of the instructor. D. S¯ğll, M. Gerstein, M. Snyder.
Molecular Biophysics and Biochemistry 800a, Molecular Mechanisms of Disease.
This course describes selected medical applications of recent findings in the
biochemical properties of biomolecules and their interactions. R. G. Shulman,
W. Konigsberg, A. Miranker, D. S¯ğll.
Molecular Biophysics and Biochemistry 900a or 901b, Reading Course in Biophysics.
Directed reading course in biophysics. Term paper required. To be arranged with
faculty.
Molecular Biophysics and Biochemistry 902a or 903b, Reading Course in Molecular
Genetics. Directed reading course in molecular genetics. Term paper required.
To be arranged with faculty.
Molecular Biophysics and Biochemistry 904a or 905b, Reading Course in Biochemistry.
Directed reading course in biochemistry. Term paper required. To be arranged
with faculty.
Neurobiology
Office: SHM C303, 785.4323
Professors
C. J. Barnstable (Ophthalmology), B. S. Bunney (Psychiatry), N. W. Daw (Ophthalmology),
P. S. Goldman-Rakic, C. Greer (Neurosurgery), S. Hockfield (Dean, Graduate School),
J. Kocsis (Neurology), R. H. LaMotte (Anesthesiology), C. Leranth (Obstetrics
and Gynecology), D. A. McCormick, P. Rakic (Chair), J. Santos-Sacchi (Surgery),
I. R. Schwartz (Surgery), G. M. Shepherd, S. G. Waxman (Neurology)
Associate Professors
M. Alreja (Psychiatry), A. Arnsten (Director of Graduate Studies), C. Bruce,
N. de Lanerolle (Neurosurgery), T. Horvath (Obstetrics and Gynecology), T. Hughes
(Ophthalmology), B. Moghaddam (Psychiatry), M. Picciotto (Psychiatry), M. Schwartz
(Director of Medical Studies), S. Strittmatter (Neurology), F. Vaccarino (Child
Study Center)
Assistant Professors
H. Blumenfeld (Neurology), W. Chen, M. Donoghue-Velleca, R. Fitzsimonds (Cellular
and Molecular Physiology), A. Roe, N. Tian (Ophthalmology and Visual Science),
M. Yeckel
Associate Research Scientists
S. Antic, S. Castner, H. Friedman, Z. Khan, M. Ma, R. Matthews, L. Selemon,
E. Sybirska, G. Williams
Postdoctoral Associates & Fellows
A. Antic, P. Atluri, B. Berechid, J. Bergsman, C. Broberger, L. Chen, C. Constantinidis,
G. Cousens, C. Crasto, A. Davison, M. Dino, J. Fitzpatrick, W. Gao, D. Gelowitz,
C. Ghandi, V. Gluncic, X. Grosmaitre, T. Haydar, B. Heider, S. Janusonis, T.
Koos, E. Markakis, M. Migliore, T. Morse, L. Negyessy, I. Opris, E. Procyk,
B. Ramsden, N. Sestan, Y. Shu, M. Viapiano, M. Wang, Y. Wang, W. Xiong, H. Zhou,
Z. Zhou
Neurobiology 500b, Structural and Functional Organization of the Human Nervous
System. An integrative overview of the structure and function of the human
brain as it pertains to major neurological and psychiatric disorders. Neuroanatomy,
neurophysiology, and clinical correlations are interrelated to provide essential
background in the neurosciences. Lectures in neurocytology and neuroanatomy
survey neuronal organization in the human brain, with emphasis on long fiber
tracts related to clinical neurology. Weekly three-hour laboratory sessions
devoted to neuroanatomy in which students dissect the human brain and examine
histological sections in close collaboration with faculty members. Lectures
in neurophysiology cover various aspects of neural function at the cellular
level, with a strong emphasis on the mammalian nervous system. Each student
may participate in a weekly physiology conference with a faculty member, covering
such topics as vision, sensory physiology, motor systems, simple nervous systems,
or general neurophysiology. Clinical correlations consist of eight sessions
given by one or two faculty members representing both basic and clinical sciences.
These sessions relate neurological symptoms to cellular processes in various
diseases of the brain. P. Rakic, M. Schwartz, and staff of the section of Neurobiology
with participation of the departments of Anesthesiology, Neurology, Neurosurgery,
Physiology, and Psychiatry.
Neuroscience 501a, Principles of Neuroscience. A lecture survey course
given jointly by the faculty of the Yale Interdepartmental Graduate Program
in Neuroscience as the introductory core course for this program. Each lecture
attempts to elucidate a major principle of nervous system development, structure,
or function. The lectures are arranged in a sequence of five sections: cellular
and molecular neurobiology, neurotransmitters and neuromodulators, development,
neural systems, and neural basis of behavior. Topics include molecular structure
of ion channels, single channel recording and monoclonal antibodies; synaptic
transmission, second-messengers and neuropeptides; synaptogenesis; functional
organization of the visual, somatosensory, and olfactory systems; and the cellular
basis of behavior, including learning and memory. A short paper is required
in each of the five main sections. M. Picciotto, R. Fitzsimonds.
Neurobiology 502a, Structure and Function of Neocortex. This seminar/lecture
course covers anatomical, biochemical, and physiological organization of selected
sensory, motor, and association regions of cortex. Sample topics discussed include
development, evolution of multiple representations, columnar organization, and
plasticity of neocortex. Permission of instructor required. P. S. Goldman-Rakic.
Neurobiology 507b/Neurology 108b/Neuroscience 507b, Cellular and Molecular
Mechanisms of Neurologic Disease. Molecular and cellular neuroscience has
recently developed many novel and powerful techniques for understanding nervous
system function. The course focuses on how these basic science advances have
been translated into breakthroughs in clinical neurology. Lectures illustrate
the connection of modern laboratory studies to our understanding of pathophysiologic
mechanisms, to the development of diagnostic tests, and to the use of novel
treatment modalities. S. Strittmatter, S. Waxman.
Neurobiology 509b, Synaptic Organization of the Nervous System. Introduction
to principles of neural circuit organization at the cellular level (morphology,
physiology, and pharmacology). Emphasis is on mammalian systems and comparisons
with lower vertebrates and invertebrates. Permission of instructor required.
G. Shepherd.
Neurobiology 510, Introduction to Methods in Cellular and Molecular Neurobiology.
Firsthand insight into various techniques and approaches used in neuroscience.
Light microscopic techniques include various metallic impregnation methods,
autoradiography, anterograde and retrograde axonal transport methods, hybridoma
and recombined DNA technology, deoxyglucose metabolic method, fluorescent and
immunocytochemical methods. Electron microscopy encompasses transmission, electronmicroscopic
autoradiography, and immunoperoxidase methodology. Choice of techniques and
hours to be arranged with individual faculty or staff members of the section
of Neurobiology.
Neurobiology 511, Introduction to Techniques Used in Electrophysiological
Analysis at the Cellular Level. Includes practical training in in vivo and
in vitro nervous system preparations, extracellular and intracellular recordings,
sensory stimulation, dye injections, and selected neuropharmacological procedures.
Choice of techniques and hours to be arranged with individual faculty or staff
members of the section of Neurobiology.
Neurobiology 520a, Vision: Cellular and Network Dynamics of the Cerebral
Cortex. This class explores the mechanisms of cerebral cortical function
through the eyes of the visual cortex. The course covers the cellular and synaptic
properties of cortical neurons and circuits and the theoretical and experimental
mechanism by which cortical neurons analyze the visual scene, including higher
order visual processes such as the analysis of color, contours, depth, motion,
and mechanisms of attention and visual memory. A. Roe.
Neurobiology 524b/Neuroscience 514b, The Regulation of Cell Fate During
CNS Development. This course is intended to discuss the general mechanisms
that regulate cell fate during the development of the central nervous system.
It focuses on the progressive specialization of cellular function beginning
with the establishment of CNS polary, the acquisition of regional identity,
and the determination of the fate of neural cells within the CNS. The interactions
between evolutionary conserved genes and intercellular signaling systems are
emphasized. The course meets twice a week for one hour each time. Each week
covers one topic as detailed in the syllabus. On Wednesday, general concepts
are reviewed in a seminar format, led by the course director, faculty participants,
or invited speakers. On Fridays, one or two papers presented by students are
discussed in detail. All class members are invited to participate in the paper
presentation and discussion. F. M. Vaccarino.
Neurobiology 530b, Neurobiology of Schizophrenia. Schizophrenia is a
debilitating disorder of thought and affect with unknown etiology. In this course,
research findings from basic and clinical venues are discussed to provide an
overview of the current state of our knowledge about the pathophysiology of
this disease and treatment strategies. The course consists of didactic lectures
and student-led discussion of key research papers that focus on morphological,
developmental, and genetic abnormalities that are suspected to occur in schizophrenia,
as well as the utility of various animal models for improving clinical treatment.
B. Moghaddam.
Neurobiology 601, Topics in Olfactory Physiology. Advanced seminar course.
G. Shepherd.
Neurobiology 610b, Fundamentals in Neurophysiology. This course is designed
for students who wish to gain a theoretical and practical knowledge of modern
neurophysiology. Graduate students specializing in neurophysiology and non-neurophysiology
are encouraged to attend, as the course begins at a very basic level and progresses
to more complicated topics. Topics include properties of ion channels, firing
properties of neurons, synaptic transmission, and neurophysiology methodology.
V. Pieribone, F. Sigworth.
Neurobiology 720a, Neurbiology. Examination of the excitability of the
nerve cell membrane provides a starting point for the study of molecular, cellular,
and intracellular mechanisms underlying the generation and control of behavior.
H. Keshishian, R. Wyman.
Neurology
Office: LCI 708, 785.4086
Professors
T. Allison (Emeritus), J. Booss, M. B. Bracken (Epidemiology and Public Health),
L. M. Brass, G. H. Glaser (Emeritus), P. Goldman-Rakic (Neurobiology), J. D.
Kocsis (Director of Postdoctoral Studies), R. H. Mattson (Director of Medical
Studies), W. I. McDonald (Adjunct), L. R. Ment (Pediatrics), J. W. Prichard
(Emeritus), P. Rakic (Chair, Neurobiology), B. A. Shaywitz (Pediatrics), S.
S. Spencer, P. Strittmatter (Visiting), S. G. Waxman (Chair)
Associate Professors
J. M. Goldstein, R. G. Kalb, R. D. Kerns (Psychiatry), E. Novotny (Pediatrics),
O. A. C. Petroff, G. B. Richerson (Director, Neurology Residency Program), S.
M. Strittmatter, T. L. Vollmer (Vice Chair, Clinical Affairs and Practice Development)
Assistant Professors
H. Blumenfeld, T. Cummins, F. Hisama, S. Markovic-Plese, D. Navaratnam, S. Novella,
H. Patwa, M. A. Rizzo, P. K. Stys (Visiting), J. L. Thompson
Instructors
C. Bradley, A. Halpern, A. L. Paige, V. Shen, D. Tinklepaugh
Research Scientists
J. A. Black, M. Craner (Visiting), S. Dib-Hajj, M. Hines (Computer Science)
Associate Research Scientists
S. Agulian, S. Bradley, M. Carrithers, L. Errante, B. Everill, V.-R. Gazula,
O. Hadjimichael, F. Inglis, K. Lankford, C. Liu, C.-N. Liu, A. Lo, W. Ni, J.
Preiningerova, M. Renganathan, D. Story, D. Tkeshelashvili, W. Wang, F. A. White,
H. Zaveri
Clinical Professors
T. N. Byrne, R. L. Lesser (Ophthalmology and Visual Science), L. Levy, T. J.
Walsh (Ophthalmology and Visual Science)
Associate Clinical Professors
R. C. Delaney, S. Levy (Pediatrics), J. C. Moench, K. N. Sena, N. M. Sussman,
F. Testa (Pediatrics), R. S. K. Young (Pediatrics)
Assistant Clinical Professors
A. R. Bobowick, S. L. Bridgers II, J. B. Butler, W. A. Camp, J. B. Guarnaccia,
B. B. Haak, M. Hasbani, A. Katz, M. W. Kremenitzer, J. H. Mashman, J. C. McVeety,
R. A. Novelly, A. M. Rapoport, D. S. Russell (Psychiatry), B. S. Russman, M.
J. Stransky, S. Tepper, F. Testa (Pediatrics), J. S. Tucker, N. Werdiger
Clinical Instructors
T. E. Conley, R. P. Einbinder, B. Greenspan, A. Mednick, D. J. Shiling, I. Silverman,
K. Taylor, E. S. Tucker, P. Wade, D. Wirz
Postdoctoral Fellows
Y. Akiyama, A. Elhabazi, A. Fournier, R. Herzog, B. P. Liu, D. K. Nguyen, B.
Shah, S. Singh, H. A. Tokuno, J. Yim, M. Zaahtreh
Postdoctoral Associates
Y. Hu, S. Li, H. Nersesyan, X. Nie, K. Tanabe, P. K. Tekumallah, H. Togashi,
X. Wang, Y. Wu
Lecturers
L. Bangalore, O. Hommo, T. Imaizumi, F. Richardson, B. R. Ritchie (Pediatrics)
Neurology 102, Clinical Neuroscience Core Clerkship. The primary goal
of this four-week clinical clerkship is to provide students with a fundamental
approach to the nervous system. Specifically, this means the history, examination,
diagnostic imaging, and treatment in the context of specific patients. Additionally,
there is a series of lectures covering the broad range of conditions students
are likely to encounter, such as trauma, stroke, infections, tumors, dementias,
and seizures. Students take call with neurology residents once a week at Yale-New
Haven Hospital; students assigned to neurosurgery take call with the residents
on that service. An ophthalmology component is integrated into the clerkship.
Students meet twice during the clerkship for basic ophthalmology lectures and
demonstrations, have opportunity once during the clerkship to examine patients
in clinic, and have an option to take call with an ophthalmology resident. After
having given input on their preferences, students are placed on one of the following
Y-NHH services for their clerkships: adult inpatient neurology, adult neurology
consultation service, pediatric neurology, neurosurgery, or a rotation consisting
of all outpatient clinics. An adult neurology rotation is also offered at the
Veterans Affairs Connecticut Health Care System, West Haven. There are only
two or occasionally three students assigned to each service, except pediatric
neurology, which is limited to one student. All rotations are done at Y-NHH
or the Veterans Affairs Connecticut Health Care System, West Haven, unless special
or unusual circumstances justify taking the course at some other academic institution.
R. H. Mattson, L. Ment, C. Duncan, P. Gloor.
Neurology 103, Clinical Neurology Elective. Assignments for the clinical
neurology elective are to the Y-NHH neurology consultation service, a rotation
consisting of all outpatient clinics; or to the neurology consultation service
at the Veterans Affairs Connecticut Health Care System, West Haven. Four-week
blocks coinciding with clerkship dates are preferred, but scheduling of electives
is somewhat flexible. Students are able to request a choice, but assignment
is made to assure that there is a balanced distribution between students in
the required Neuroscience Clerkship and those doing electives, in order to allow
an optimal learning experience for all students. Students work directly with
attending faculty, chief residents, and junior residents as well as other medical
students, rotators, and support staff. In addition to in-hospital patient evaluation
and care, students on a consultation service are assigned to outpatient clinics.
The students participate in departmental conferences and seminars. In addition,
participation in most of the activities of the required Neuroscience Clerkship
(e.g., didactic lectures, ophthalmology) is encouraged (see Neurology 102 for
description of clerkship details). The department is receptive to other specially
tailored programs in areas such as epilepsy, stroke, movement disorders, neuroimmunology,
etc., as well as clinical neurophysiology and research methods. R. H. Mattson
and associates.
Neurology 104, Clinical Neurology Subinternship. Under appropriate supervision,
students directly examine, diagnose, and manage patients on the neurology services
at Yale-New Haven Hospital or Veterans Affairs Connecticut Health Care System,
West Haven, and attend daily teaching rounds and conferences. Hours to be arranged.
Four-week rotations are recommended; alternative services are possible. Limited
to two students each period, usually one on each service. R. H. Mattson and
associates.
Neurology 106b, Clinical Neurophysiology. Seminars and demonstrations
in clinical applications of neurophysiology: electromyography and electroencephalography.
Basic electronics are taught along with standard practice of recording and interpreting
neurophysiology studies. J. M. Goldstein, H. S. Patwa, S. P. Novella.
Neurology 108b/Neurobiology 507b/Neuroscience 507b, Cellular and Molecular
Mechanisms of Neurologic Disease. Molecular and cellular neuroscience has
recently developed many novel and powerful techniques for understanding nervous
system function. This course focuses on how these basic science advances have
been translated into breakthroughs in clinical neurology. Lectures illustrate
the connection of modern laboratory studies to our understanding of pathophysiologic
mechanisms, to the development of diagnostic tests, and to the use of novel
treatment modalities. S. Strittmatter, S. Waxman.
Neurology 112b, Neuro-Oncology. Neurological complications occur in
approximately 20 percent of hospitalized oncology patients. The neurological
complications of systemic cancer, as well as of primary CNS tumors, are discussed
in depth. Issues regarding diagnosis and management of metastatic disease involving
the nervous system as well as treatment-related complications are reviewed.
In addition, metabolic and vascular disturbances and infections unique to the
oncology patient that involve the nervous system are discussed. Specific cases
are presented and arrangements are made to see specific patients during the
elective period. This course is offered every three weeks with two lectures
each week and is limited to three or four students per session. T. N. Byrne.
Neurology 114b, Physiology of the Mammalian Nervous System. The overall
objective of this laboratory course is to introduce the student by hands-on
experience to a variety of cellular electrophysiological techniques used in
the study of the mammalian nervous system. Students set up a small electrophysiology
laboratory and carry out experiments with the supervision of faculty. Laboratories
include sucrose gap in whole nerve, single microelectrode current and voltage
clamp recording of sensory neurons, field potential studies in rat hippocampal
slice, and patch clamp analysis of cultured neurons. This course is limited
to six to eight students. Permission of instructor is required for enrollment,
203.937.3802. J. D. Kocsis.
Neurosurgery
Office: TMP 4, 785.2805
Professors
R. Bronen (Diagnostic Radiology), W. F. Collins (Emeritus), C. C. Duncan, C.
A. Greer, C. LaMotte, J. Persing (Surgery/Plastic), J. M. Piepmeier, D. E. Redmond
(Psychiatry), D. D. Spencer (Chair), A. Van den Pol
Associate Professors
R. T. Constable (Diagnostic Radiology), N. de Lanerolle, A. C. de Lotbinière,
M. Westerveld, A. Williamson
Assistant Professors
J. Bartolomei, A. Bordey, V. Chiang, M. Gunel, K. Stoddard, J. Strugar, K. Vives
Associate Research Scientists
T. Eid, X.-B. Gao, P. K. Ghosh, C. Livsey, P. R. Patrylo, H. Treloar, K. Wu
Visiting Research Scientists
H. Hetherington, J. Pan
Research Affiliates
R. B. Duckrow, E. R. O'Connor, J. Pizzonia
Clinical Professors
L. M. Davey, F. Robinson
Associate Clinical Professors
I. Goodrich, D. E. Nijensohn
Assistant Clinical Professors
T. J. Arkins, G. M. Bloomgarden, P. S. Dickey, Z. Ghogawala, E. Kornel, T. Lansen,
C. W. Needham, J. K. Sabshin, J. Stern
Clinical Instructors
E. Akeyson, A. Firlik
Postdoctoral Associate
Y. Li
Postdoctoral Fellows
R. Buchanan, C. Iwema, K. Mishra, M. Noha, L. Rondeau-Barakat
Lecturer
E. M. Ogle
Neurosurgery 101, Neurological Surgery. This is an externship in which
the student is involved in inpatient evaluation, outpatient visits, supervised
emergency and inpatient consultations. The student attends the operating room,
follows patients, and is expected to correlate the clinical experience with
basic neuroscience. Limited to two students. J. Bartolomei, V. Chiang, W. F.
Collins, A. de Lotbinière, C. C. Duncan, M. Gunel, J. M. Piepmeier, D.
D. Spencer, J. Strugar.
Neurosurgery 102, Experimental Neurological Surgery. Typically taken
during completion of the thesis requirement. Specific projects are by agreement
with faculty members. Ongoing laboratory research includes: the immunohistochemical
assessment of the epileptic focus (N. C. de Lanerolle); ultrastructural assessment
of organization and plasticity in local synaptic networks (C. A. Greer); the
distribution and specificity of membrane-bound proteins directing neuronal growth
(A. Van den Pol); human and animal slice electrophysiology (A. Williamson, A.
Bordey); human and animal intracerebral microdialysis (D. Spencer, I. Cavus);
image-guided neurosurgical robotics and biophysical studies of brain imaging
(D. Spencer, J. Duncan); molecular genetics of neurological disease (M. Gunel);
role of the gene Notch in neoplastic CNS tumors (K. Vives); characterization
of ensheathing cells in promoting axonal elongation (J. Bartolomei). Clinical
research includes neurotrauma (V. Chiang), neuropsychological studies (M. Westerveld,
K. Stoddard), spine disease (J. Strugar, J. Bartolomei), epilepsy surgery (D.
Spencer), pediatric neurosurgery outcomes (C. Duncan), neuro-oncology (J. Piepmeier),
and stereotactic radiosurgery (A. de Lotbinière). Available throughout
the year. Arrangements made with C. A. Greer.
Obstetrics and Gynecology
Office: FMB 339, 785.4002
Professors
H. R. Behrman, M. B. Bracken (Epidemiology), G. Burrow (Internal Medicine),
S. K. Chambers, J. Copel, R. A. Ehrenkrantz (Pediatrics), I. Gross (Pediatrics),
J. Hayslett (Internal Medicine), R. B. Hochberg, E. E. Jones (Director of Medical
Studies), B. M. Kacinski (Therapeutic Radiology), E. I. Kohorn (Emeritus), C.
Leranth, M. Mahoney (Genetics), S. McCarthy (Diagnostic Radiology), F. Naftolin
(Molecular, Cellular, and Developmental Biology), P. M. Sarrel (Psychiatry),
P. E. Schwartz, K. Taylor (Diagnostic Radiology)
Associate Professors
A. Arici, R. Bahado-Singh, A. Duleba, R. Feinberg (Adjunct), F. Galerneau, J.
Henrich (Internal Medicine), T. Horvath, U. Magriples, V. Parkash (Pathology),
T. Rutherford, E. Sze, K. Williams
Assistant Professors
S. Diano-Horvath, G. Mor, D. Sakkas, H. Taylor
Instructors
R. Al-Rejjal, R. Benoit, G. Daftary, P. Matta, N. Mahutte, J. Murphy, D. Neale,
T. Ozcan, T. Pejovic, V. Ravishankar, E. Seli, M. Small, M. Snyder, J. Tangir,
E. Toy
Senior Research Scientist
G. Huszar
Research Scientist
H. Kliman
Associate Research Scientists
E. Borok, O. Hadjimichael, D. Labaree, J. Song
Research Affiliates
L. Cole, D. Keefe, A. Palumbo, F. Parikh, T. Polcz, S. Rotmensch, D. Seifer,
P. Whitten
Clinical Professors
M. Berman, S. Lavietes, V. Lynch, M. Minkin, W. Reguero, M. Schiffer, S. Spangler,
L. Wartel
Associate Clinical Professors
R. Auerbach, H. Blanchette, C. Cassin, R. Cwik, D. Greenfeld, T. Hanson, M.
Holley, R. Kaump, W. Lieber, C. McCarthy, L. Olson, L. Silberman, J. Silidker,
B. Silverman, H. Simon, V. Stuermer, R. Vidone, J. Whetham, L. Zamore
Assistant Clinical Professors
N. Achong-Dorvilus, J. Asis, M. Beatrice, E. Brennan, P. Brines, S. Casper,
E. Chang, R. Chosak, I. Cohen, P. Coppola, P. Dennen, E. Fine, K. Fletcher,
D. Fox, G. Foye, M. Gillette, C. Kandall, E. Karlovsky, J. Karsh, K. Kearns,
K. Kharma, J. Knudson, T. Kumarasamy, S. Laifer, P. Lamastra, B. Lieberman,
E. Luchansky, J. Lyddy, B. McDowell, L. Plisic, P. Ramirez, N. Ravski, S. Richman,
B. Rigney, S. Roth, R. L. Starace-Colabella, R. Stiller, A. Strong, H. Suesserman,
E. Topran
Clinical Instructors
A. Asis, M. Asis, E. Berry, U. Bhuvanesh, S. Bowers, A. Chelouche, F. Cohn,
S. Curet-Rivera, S. Dolan, S. Fleischman, M. Gatter, J. Grosso, C. Huttler,
J. Kaczmarek, A. Landry, D. Lima, H. Lope De Haro, R. Lubell, B. Maloy, J. McGrade,
I. Morais, R. Moscarelli, H. Nusbaum, E. Palluotto, A. Petruzzelli, R. Pringle,
K. Rath, M. Rhee, S. Rosenman, A. Ross, R. Samuelson, M. Speranza, J. Stadalnik,
A. Tirado, D. Tonzola, M. Tse
Postdoctoral Fellows
F. Abushahin, E. Amama, P. Grases Briceno, S. J. Choi, A. Ergur, H. Gaafer,
S. Gain, K. Heung-Yeol, M. Kamsteeg-Lemstra, M. Karaca, U. Kayisli, C. Kocer,
C. Lim, Y. Nastaran-Foyouzi, A. Sauiu, F. Selam, I. Silva
Postdoctoral Associates
C. Celik, S. Ggo, A. Jakab, J. Zhang
Lecturers
M. Davis, B. Forbis, N. Kellett, G. Kolin, V. McEvoy, L. Mosley, D. Quealy,
M. Reault, T. Santos, E. Shawn, J. Vulte
Obstetrics and Gynecology 103, Core Inpatient Clerkship. This core clerkship
is a four-week rotation in which students serve as clinical clerks on both the
obstetrics (two weeks) and the gynecology services (two weeks). At our affiliate
sites, which include Bridgeport Hospital, Hospital of St. Raphael, and Danbury
Hospital, the clerk functions as part of a team that participates in both gynecologic
and obstetrical care. During the obstetrics portion of the rotation at Yale-New
Haven Hospital, the clinical clerk is assigned to the labor floor and is expected
to actively participate in patient care commensurate with his or her experience.
Students are expected to work up and follow patients during labor and delivery,
write notes during the intrapartum period, participate in the delivery, and
participate in the patient's postpartum care. Students on gynecology spend one
week on the general gynecology service, where they become familiar with the
common disorders encountered in gynecological practice. The student also spends
one week on the gynecologic oncology service and functions as a part of that
team. The rotation offers a unique opportunity for the student to learn preoperative
and postoperative management of patients with complicated medical problems,
review pelvic and abdominal anatomy, and become familiar with the basics of
major gynecological cancer treatment including surgical management as well as
chemotherapy and radiation therapy management. The clerk is expected to interview,
examine, and follow patients assigned in rotation. The student is also expected
to participate in operative procedures, particularly as relates to those patients
that they are responsible for following. E. E. Jones.
Obstetrics and Gynecology 104/Psychiatry 107, Shared Clerkship in Medical
Psychiatry. This clerkship, administered jointly with the Department of
Psychiatry, is designed to provide students with an understanding of the presentation
of psychiatric illness in patients with co-morbid medical disorders. Emphasis
is placed on screening interviews, including mental status examination; identification
of symptoms; and differential diagnosis and initial treatment recommendations
in patients with co-morbid and psychiatric illness. Special emphasis is placed
on evaluation of psychiatric emergencies and competency to make informed medical
decisions. R. Rohrbaugh and Department of Psychiatry faculty.
Obstetrics and Gynecology 107, Perinatal Elective. The Maternal Fetal
Medicine Division of the Department of Obstetrics and Gynecology offers a three-
to four-week high-risk obstetric elective for fourth-year medical students.
Ideally, only one student should be on the service at any time. The student
is on call with the high-risk chief resident and should come in at least on
every third to fourth night to take part in the management of high-risk patients
during labor and delivery. The student attends the high-risk obstetric clinics
that are held once a week on Thursday. In addition to doing high-risk obstetric
rounds with the team and admitting emergency patients, the student is expected
to attend perinatal ultrasound sessions that are held every day from 9 a.m.
to 4 p.m. There are several rounds for students that include all obstetric rounds
held in the department and the daily high-risk obstetric rounds. The evaluation
of the student is based primarily on the clinical performance as well as participation
at rounds and presentation of cases. J. Copel and staff.
Obstetrics and Gynecology 108, Reproductive Endocrinology and Infertility
Elective. A clinical elective in reproductive endocrinology and infertility.
Students pursuing this elective gain a basic knowledge of reproductive endocrine
function including the physiology of the menstrual cycle and ovulation, male
reproductive events, and the physiology of the climacteric and menopause. They
also are introduced to disruptions in physiology and function leading to endocrine
and infertility problems. Some of the common clinical problems to which students
are introduced are polycystic ovarian disease and other symptoms of androgen
excess, hyperprolactinemia, anovulatory syndromes, various genetic abnormalities
that affect fertility, endometriosis and its sequelae, and tubal disease and
its ramifications for surgery. In addition, students are exposed to the new
reproductive technology such as in vitro fertilization and the embryo transfer
procedure. By the end of the elective, students are expected to be knowledgeable
in all of the above areas through both reading and interaction with patients,
faculty, and fellows. Suggested reading for the elective is Speroff, Glass,
and Kase, Clinical Gynecologic Endocrinology and Infertility, 6th edition, Williams
and Wilkins, publishers. In addition to being conversant with the above clinical
situations, students on elective are expected to see endocrine and infertility
patients in the clinic with faculty and fellows. Patients are interviewed and
presented to the faculty member working with the students, and the cases are
discussed. If appropriate, students also participate in physical examinations.
Students are also expected to participate in surgical procedures on endocrine
and infertility patients. Students take histories and perform physical examinations
on major surgical cases at the time of hospital admission. They are expected
to be present in the operating room during the surgery and follow the patients
during the postoperative recovery period. Students also have the opportunity
to assist in outpatient surgical procedures done in the one-day surgical center
and to observe procedures in in vitro fertilization and the embryo transfer
program. A full range of conferences and teaching sessions including the Obstetric
and Gynecologic Grand Rounds also is available for students participating in
the elective. Staff.
Obstetrics and Gynecology 109, Oncology Elective. The purpose of the
oncology elective is to enhance the student's knowledge of the diagnosis and
management of women with gynecologic malignancies. The elective is offered to
one student at a time for three to four weeks. The student is exposed to all
modalities of treatment for gynecologic malignancies including radical gynecological
surgery, chemotherapy, and radiation therapy. The student is expected to be
an integral part of the team in the management of the patients admitted to the
service. The student admits patients and takes part in their care throughout
the elective period. The student is assigned to the operating room, especially
to assist the patient whom he or she has evaluated. In addition, the student
attends one-day surgical procedures to observe the placement of brachytherapy
and other procedures, e.g., cystoscopy, proctoscopy examination under anesthesia
with biopsy. In the ambulatory setting, the student is exposed to the gestational
trophoblastic clinic and the colposcopy clinic. A multiple-discipline tumor
conference including faculty members from the divisions of Radiation Oncology
and Gynecologic Pathology is held weekly. The student is also expected to attend
a weekly gynecologic oncology conference and participate in the discussion.
P. E. Schwartz and staff.
Obstetrics and Gynecology 197/Internal Medicine 197/Psychiatry 297, Multidisciplinary
Approach to Women's Health. This course, run by the departments of Internal
Medicine, Obstetrics and Gynecology, and Psychiatry, offers a multidisciplinary
approach to gender-specific health issues across the life span of women. Inherent
in the model is a focus on the total health of each patient. Two days per week
are devoted to independent study and twelve didactic case-based sessions on
topics including domestic violence, contraception, medical complications of
pregnancy, breast cancer, menopause, osteoporosis, cardiovascular disease, and
epidemiology and prevention in the health of women. Most didactic sessions are
led by several experts on the topic, each representing his or her own discipline.
Clinical sessions are preceded by an intensive review of the breast and pelvic
exam led by professional teaching models. Three days per week are devoted to
clinical experiences that allow students to assess women patients within primary
care, gynecology, and psychiatric settings, as well as to be involved in specialty
areas such as pregnancy termination (optional), breast clinic, cardiac wellness,
mammography, and bone density. This course meets the requirements for the Primary
Care Clerkship or can be taken as an elective. Not offered every month. Open
on a first-come first-served or a lottery basis. K. P. White (Internal Medicine),
E. E. Jones (Obstetrics and Gynecology), R. M. Rohrbaugh (Psychiatry).
Ophthalmology and Visual Science
Office: BB 110, 785.2020
Professors
C. Barnstable, M. Coca-Prados, N. Daw, C. Gonzalez, W. H. Miller (Emeritus),
M. L. Sears, M. B. Shields (Chair)
Associate Professors
T. Hughes, L. J. Rizzolo (Surgery), J. Sinard (Pathology)
Assistant Professors
B. DeBroff, S. Forster, Z. Klett, G. Shafranov, S. Tauber, N. Tian, C. Zeiss
(Comparative Medicine)
Instructor
K. Chaudhri
Associate Research Scientist
S. Ghosh
Clinical Professors
I. W. Abrahams, R. O. Howard, A. A. Khodadoust, R. L. Lesser, D. E. Silverstone,
T. J. Walsh, A. S. Wong
Associate Clinical Professors
M. L. Fezza, P. Haffner, A. J. Levada, D. W. Parke, K. M. Stoessel, R. A. Wiznia
Assistant Clinical Professors
P. Branden, J. Elman, P. Falcone, A. J. Fezza, K. Gagnon, S. B. Hersh, W. Larrison,
D. W. MacRae, A. Mead, M. Milner, J. Olson, A. D. Pearlstone, E. A. Petrelli,
R. L. Petrelli, A. Romania, A. Rose, C. Sklar, S. M. Soloway, R. G. Sweeting,
M. L. Weitzman, B. D. Zuckerman
Clinical Instructors
D. Bacal, J. Q. Brooks, S. Castracane, V. DeLuise, A. R. Ecker, P. A. Ecker,
P. Guida, E. Lim, J. Martone, P. Masi, M. C. Ruchman, D. Shore, J. Silverman,
P. Silverstone, J. Sokol, J. Weisz
Postdoctoral Fellow
R. Reddy
Postdoctoral Associates
Q. Fischer, Q. He, Y. Li, S. Liu
Ophthalmology and Visual Science 103, Clerkship in Clinical Ophthalmology.
This required clerkship in clinical ophthalmology is given over several afternoons
during the Neuroscience Clerkship. The objective of the clerkship is to convey
the basic knowledge and examination skills required to diagnose and initiate
treatment for common and urgent disorders of the eye and visual system. Instruction
is through required readings, seminars, case study material, a practice examination
session, and clinic sessions at either the Yale Department of Ophthalmology
and Visual Science, the Veterans Affairs Connecticut Health Care System, West
Haven, or a community ophthalmologist's office. S. Forster.
Ophthalmology and Visual Science 120, Elective in Clinical Ophthalmology.
This intensive two-week elective consists of twenty half-day sessions during
which the students observe in subspecialty clinics, evaluate patients in general
ophthalmology clinics, observe ophthalmic surgery, participate in department
conferences, and review independent study material provided by the department.
Subspecialty experiences include corneal and external eye diseases, glaucoma,
neuro-ophthalmology, oculoplastics, and retinal diseases. Each two-week elective
is limited to two fourth-year students. Offered September through May. S. Forster,
faculty, and resident staff.
Ophthalmology and Visual Science 126, Preceptorial in Ophthalmology.
In this elective the student has intensive exposure to one ophthalmic subspecialty
under the direct supervision of one or two faculty members. Generally, the experience
includes observing in a subspecialty clinic and the operating room, and may
include completion of a minor research project. Prior to starting this elective,
the student must have outlined a plan of study and obtained the approval of
the supervising faculty members. Faculty members in corneal and external diseases,
glaucoma, oculoplastics, and retina participate. A list is available from the
director of medical studies. Limited to fourth-year students. One to four weeks.
Offered September through June. Faculty.
Orthopaedics and Rehabilitation
Office: YPB 133, 785.2579
Professors
R. Baron, G. Friedlaender (Chair), C. Gundberg, M. Horowitz, P. Jokl, M. Panjabi,
R. Pelker, T. Renshaw, W. Southwick (Emeritus)
Associate Professors
M. Baumgaertner, J. Cholewicki, L. Katz (Diagnostic Radiology), J. S. Marsh,
J. Slade, A. Vignery
Instructors
J. Beiner, J. Grauer, R. Pavlovich, P. Sethi, S. Tomak
Research Scientist
W. Horne
Associate Research Scientists
A. Bruzzaniti, G. Sabatakos, A. Sanjay
Clinical Professors
P. Brown, O. Chrisman (Retired), K. Keggi, J. Lynch, U. Weil
Associate Clinical Professors
H. Bradburn, R. Deponte, A. Goodman, R. Johnson, R. Margolis, E. Sella
Assistant Clinical Professors
J. Aversa, A. Axtmayer, R. Bernstein, P. Blume, D. Caminear, J. Daigneault,
P. DeLuca, R. Eisen (Pathology), D. Gibson, G. Gorecki, J. Irving, J. Kaplan,
J. Kelley, K. Kramer, J. Lieponis, M. Luchini, P. Luchini, R. Mayor, M. Murphy,
D. Novicki, T. Patel, M. Pressman, J. Raycroft, A. Reznik, D. Rosenblum, J.
Shine, A. Sicklick, M. Silver, J. Sumner, C. Swigart, G. Taggart, J. Wu
Clinical Instructors
C. Barrette, D. Bindelglass, D. Brittis, M. Clain, R. Dawe, R. Diana, A. H.
Feldman, R. Hendrikson, H. Hermele, N. Kaplan, J. Mangieri, J. McCallum, T.
Moran, M. Morrison, P. Naiman, J. Perlman, R. Stanton, P. Stovell
Lecturer
M. Parisi
Orthopaedics and Rehabilitation 102, Surgical Clerkship. Twelve weeks
total. Students in the first clinical year spend six weeks on the general surgical
service of one of the following: Yale-New Haven Hospital, Veterans Affairs Connecticut
Health Care System, West Haven, or Hospital of St. Raphael. Each student is
integrated into the clinical team and assigned to specific patients. Responsibilities
include taking histories and performing physical examinations on their patients,
participating in the evaluation and management of these patients, following
patients' progress, and participating as assistants in the surgical operations
performed upon their assigned cases. In addition, the students are expected
to participate in the evaluation and care of the critically ill patient in the
intensive care unit and the injured patient in the emergency room. Emphasis
is placed on involving students in the process of clinical problem solving with
the guidance of the residents and the attending preceptors. Conferences, case
study groups, and rounds are held emphasizing this problem-oriented approach.
Staff.
The remaining six-week period is spent as a clinical clerk in the surgical specialties. Seven specialties are offered: cardiothoracic, otolaryngology, neurosurgery, orthopaedics, pediatric, plastic and reconstructive, and urology. Each student elects three of these specialties and spends two weeks on each. While on the specialty of choice, the student is assigned patients in rotation and carries out complete histories, physical examinations, and certain procedures on these patients. While on the orthopaedic service, the student is assigned to one of the subspecialty teams, which include pediatric orthopaedics, spine, joint reconstruction, trauma, oncology, foot and ankle, hand, and sports medicine. The student is expected to participate, whenever possible, in the operative procedures performed on these patients and in their postoperative care. The student is also invited to attend the outpatient clinics in his or her assigned specialty. A series of one-hour lectures, rounds, or demonstrations is given each afternoon by the surgical specialties so that the student has the opportunity of gaining knowledge of the wide field of specialties even though he or she does not participate in every specialty as a clinical clerk. Directed by individual surgical specialty chiefs.
Orthopaedics and Rehabilitation 104, Subinternship. Limited to third-
and fourth-clinical years, with prior clerkship rotation. The student is an
active member of one of the orthopaedic teaching teams (pediatric orthopaedics,
spine, joint reconstruction, trauma, oncology, foot and ankle, hand, and sports
medicine). Inpatient, outpatient, and operating room experience is supplemented
by regular conferences. Limited to four students, preferably for one-month rotations,
throughout the year. Arrangements must be made with Kathryn Umlauf.
Orthopaedics and Rehabilitation 108, Subinternship, Adult Reconstructive
and Rehabilitative Orthopaedics, Veterans Affairs Connecticut Health Care System,
West Haven. The student functions as the intern on a large adult orthopaedic
service. He or she attends conferences at the Veterans Affairs Connecticut Health
Care System, West Haven, and at Yale-New Haven Hospital. (Y-NHH conferences
include an ongoing seminar on basic sciences as related to the musculoskeletal
diseases. ) The student is a full participant in the outpatient department and
in the work of the operating room. This subinternship offers an intensive clinical
experience with a variety of complex orthopaedic reconstructive problems. Rotations
are usually for one month. By arrangement with Kathryn Umlauf.
Orthopaedics and Rehabilitation 110, Biomechanics Terminology. Presentation
and explanation of some basic biochemical terms used to describe body tissues,
structures, and functions. More than one hundred basic engineering terms are
introduced. The format of presentation for each term is (1) a precise definition
followed by units of measurement in the new S.I. system, (2) a detailed explanation,
and (3) examples of its use in the everyday experience as well as in the medical
field. Mathematical formations are presented whenever necessary. Eight weeks,
by arrangement. M. Panjabi.
Orthopaedics and Rehabilitation 116, Basics of (Fracture) Diagnosis and
Treatment. A six-week seminar in the basic elements of diagnosis and treatment
of a spectrum of musculoskeletal trauma. M. Baumgaertner.
Orthopaedics and Rehabilitation 118, Musculoskeletal Anatomy. The basics
of musculoskeletal anatomy from a functional anatomic and surgical perspective.
The material is presented using prosected specimens. Knowledge of Anatomy 100a
or its equivalent is assumed. M. Baumgaertner.
Orthopaedics and Rehabilitation 120, Rehabilitation Medicine at Gaylord
Hospital. A four-week elective rotation designed to provide a comprehensive
view of rehabilitation. The elective is composed of didactic sessions and clinical
experiences in both the inpatient and outpatient setting. Areas of primary focus
include spinal cord injury, head trauma, multiple trauma, amputations, pain
management, occupational rehabilitation, stroke, and other neurologic rehabilitation.
Specific problems, such as gait deviation, heterotropic ossification, and spasticity
are addressed. Therapeutic modalities-bracing and other durable medical equipment-are
covered. The roles of allied health professionals, including physical, occupational,
and speech therapies, and neuropsychology are demonstrated. Available throughout
the year by arrangement with A. Sicklick and D. Rosenblum.
Pathology
Office: LH 108, 785.2759
Professors
D. C. Altieri, P. W. Askenase (Internal Medicine), D. Carter, Y. Choi (Co-Vice
Chair), J. Costa (Co-Vice Chair), S. E. Downing (Emeritus), S. D. Flynn, N.
Holbrook (Internal Medicine), M. Kashgarian, J. A. Madri (Director of Medical
Studies), V. T. Marchesi, M. Mooseker (Molecular, Cellular, and Developmental
Biology), J. S. Morrow (Chair), J. S. Pober, J. K. Rose, D. F. Stern (Director
of Graduate Studies), R. Yesner (Emeritus)
Associate Professors
X.-Y. Fu, E. Glusac, R. Homer, J. Kim, D. Krause (Laboratory Medicine), L. Languino,
P. Lizardi, J. M. McNiff (Dermatology), V. Parkash, A. Perkins, M. Reyes-Mugica,
D. Rimm, M. Robert, J. Sinard, G. Tallini
Assistant Professors
M. Chacho, T. Handerson (Dermatology), L. Hao, P. Hui, D. Jain, R. Lazova (Dermatology),
I. Ocal, M. Pinto, R. G. Wells (Internal Medicine), W. Zheng
Instructors
L. Bernstein, D. Kowalski
Research Scientists
J. Brandsma (Comparative Medicine), C. Howe, D. Johnson
Associate Research Scientists
P. Biswas, R. Camp, G. Chatterjee, J. Czyzyk, D. Dillon, M. Fornaro, L. Madge,
K. Mahboubi, M. Mattie, D. Pradhan, N. Rose, M. Stankewich, Z. Walther, T. Welte,
B. Yatsula, S. Zhang, Z. Zhang
Clinical Professors
G. L. Davis, D. M. Lowell, G. Reynoso
Associate Clinical Professors
R. S. Beckett, N. E. Herrera, P. B. Hukill, S. H. Lee, D. F. Miller, I. Nash
(Laboratory Medicine), D. J. Nelligan, R. A. Vidone (Obstetrics and Gynecology),
I. M. Weisbrot
Assistant Clinical Professors
H. W. Carver, T. E. Ciesielski, E. M. Clayton, M. T. Cronin, R. Eisen, P. Fiedler
(Laboratory Medicine), N. Gelfman, G. Golenwsky, I. S. Hahn, G. M. Kleinman,
R. M. Kranwinkel, V. Lopez, D. MacRae (Ophthalmology and Visual Science)
Clinical Instructors
W. G. Frederick, D. Graesser, A. Katsnelson, S. Wain, N. Xue
Postdoctoral Associates
O. Blanc-Brude, J. J. Chen, C. Cianci, T. Dengler, X. Feng, P. Fortugno, I.
Gonzalez Garcia, O. Gribanov, S. Hamann, L. M. Hao, Z. M. Huang, A. Kano, H.
Kim, R. Krishna, J. Lage, F. Li, J. H. Li, G. Liu, T. Manes, A. McCabe, O. Mironenko,
K. Okuma, G. Reshetnikova, N. Wall, G. Watanabe, B. Xie, X. Xu, C. Zhang, S.-M.
Zhang, D.-Q. Zheng, Y. Zhou
Postdoctoral Fellows
K. Boyd, S. Curristin, O. Eickelberg, C.-F. Hu, S. Husain, K. Ivanov, A. Jackson-Fisher,
J. Jacoby, R. Khurana, D. Ladner, C.-J. Li, A. A. Meszaros, A. Roberts, S. Sardi,
P. Shukla, L. Tsvetkov, J. Wheeler, M. Yeh
Pathology 100, Pathological Basis of Human Disease. Fundamental principles
underlying the pathological alterations in function and structure that constitute
the reaction of the organism to injury. Pathology of diseases involving special
organs and systems. Correlation of the clinical and anatomical manifestations
is emphasized. J. Madri, S. Flynn, and staff.
Pathology 116, Autopsy Pathology. Participation in the autopsy service
with members of the house staff in pathology. Participation in autopsies and
the presentation and review of the clinical and anatomical findings of postmortem
examinations with senior members of the department. Opportunities exist for
correlation studies with previous biopsies, and clinical investigative and cell
biologic techniques in relation to necropsy material. Six weeks minimum, full
time. Limited to two students. J. Sinard and staff.
Pathology 117, Anatomic Pathology. The department offers an elective
to medical students in the third and fourth years which provides a broad experience
in general diagnostic techniques. Students have opportunities to participate
in surgical pathology, cytology (including fine-needle aspiration), and autopsy.
A daily conference is scheduled for both residents and students. In addition
to direct responsibilities in the handling of the cases, the student has the
opportunity to apply the special techniques of electron microscopy, immunohistochemistry,
flow cytometry, and molecular diagnostics. A minimum of four weeks is suggested
for this elective. Five students are accommodated every four to six weeks. J.
Costa and staff.
Pathology 650b, Cellular and Molecular Biology of Cancer. A comprehensive
survey of cancer research from the cellular to the clinical level. The relation
of cancer to intracellular and intercellular regulation of cell proliferation
is emphasized, as are animal models for cancer research. Background in molecular
genetics and cell biology is assumed. D. F. Stern and A. S. Perkins.
Pathology 670b, Biological Mechanisms of Reaction to Injury. An introduction
to human biology and disease as a manifestation of reaction to injury. Topics
include organ structure and function, cell injury, circulatory and inflammatory
responses, disordered physiology, and neoplasia. M. Kashgarian and staff.
Pathology 680a, Topics in Molecular Medicine. Readings and discussion
in topics relevant to cell biology, pharmacology, and molecular medicine. The
class emphasizes analysis of the primary research literature and development
of presentation skills. R. G. Wells, D. Krause.
Pathology 690b, Molecular Mechanisms of Diseases. This course focuses
on the molecular defects underlying fundamental human diseases. The program
covers the cellular and molecular mechanisms of infectious and degenerative
diseases, vascular and inflammatory processes, AIDS, and hemorrhagic disorders.
The objective is to highlight the interface between experimental and molecular
medicine, and how it relates to the pathogenesis of human diseases. D. C. Altieri
and staff.
Pediatrics
Office: LMP 4085, 785.4638
Professors
W. A. Andiman, W. R. Anyan, M. D. Baker, R. S. Baltimore, G. P. Beardsley, W.
R. Breg (Genetics; Emeritus), T. Carpenter, J. A. Copel (Obstetrics and Gynecology),
T. F. Dolan, Jr. (Emeritus), C. C. Duncan (Neurosurgery), R. A. Ehrenkranz,
M. Genel, S. Goldstein, I. Gross, J. Gryboski (Emeritus), G. G. Haddad, A. Horwich
(Genetics), M. Hostetter, R. Johnston (Adjunct), Z. Kain (Anesthesiology), D.
Kessler, D. M. Komp (Emeritus), J. Leckman, M. F. Leonard (Child Study Center;
Emeritus), J. M. Leventhal, M. Lewis (Child Study Center), G. Lister, Jr., M.
J. Mahoney (Genetics), P. L. McCarthy, L. R. Ment, I. G. Miller, M. S. Moyer,
H. A. Pearson (Emeritus), M. Rogers (Adjunct), S. Rooney, D. S. Rowe (Emeritus),
J. E. Schowalter (Child Study Center), J. H. Seashore (Surgery), M. R. Seashore
(Genetics), E. D. Shapiro, B. A. Shaywitz, S. E. Shaywitz, N. J. Siegel (Vice
Chair), J. Sinclair (Adjunct), B. Smith (Laboratory Medicine), A. J. Solnit
(Child Study Center; Emeritus), N. Talner (Emeritus), W. V. Tamborlane, R. J.
Touloukian (Surgery), F. Volkmar (Child Study Center), J. Woolston (Child Study
Center)
Associate Professors
A. Bazzy-Asaad, M. Brueckner, M. Cappello, S. Caprio, M. Egan, J. Fahey, B.
Forsyth, A. H. Friedman, P. Gallagher, K. Gaudio, J. Gruen, L. Mayes (Child
Study Center), B. McClain (Anesthesiology), E. Novotny, G. Pizzorno (Internal
Medicine), G. Plautz, B. Pober (Genetics), M. Reyes-Mugica (Pathology), S. Rivkees,
L. Rosenfeld (Internal Medicine), D. Schonfeld, R. Shiffman, J. Van Hoff, M.
Westerveld (Neurosurgery)
Assistant Professors
R. Antaya (Dermatology), L. Arnold, K. Banasiak, C. Baum, K. Bechtel, J. Calderon,
R. Chapman, E. Colson, B. Degar, S. Escalera, M. Farrell (Internal Medicine),
L. Jacobsen (Psychiatry), J. Kahn, L. Kass, C. Kim, J. Klig, P. Leith (Anesthesiology),
R. Palazzo, K. Santucci, B. Sleight, C. Snyder, J. M. Stein (Internal Medicine),
C. Weitzman
Instructors
D. Chirnomas, D. Wisler
Research Scientists
J. McGrath (Comparative Medicine), K. Pugh, Y. Xia
Associate Research Scientists
V. Bhandari, D. Bockenhauer, C. Bogue, P. Bowers, B. Chen, L. Denson, R. Douglas,
W. Echevarria, S. Frankel, K. Freudigman, R. Fuleihan, M. Gaeta, X. Gu, W. Kennedy
(Molecular Biophysics and Biochemistry), K. Marchione, J. McKinney, W. Mencl,
T. Monsod, E. Pinter, G. Porter, K. Schneider, S. Smith-Rapaport, M. Vazquez,
H. Yan, P. Zhang, Z. Zhao
Research Affiliate
E. Kennedy
Clinical Professors
M. Curnen (Epidemiology and Public Health), J. R. Gallagher (Emeritus), P. S.
Goldstein, H. Jacobs, T. Kennedy, D. Kohn (Surgery), R. A. Kramer, L. S. Krassner,
M. Kresch, R. G. LaCamera, B. M. McDonald, J. McNamara, A. C. Mermann, H. Sacks
(Child Study Center), M. Sklaire, M. A. Wessel, R. Whittemore, J. Zelson
Associate Clinical Professors
F. P. Anderson, R. Angoff, D. Beardsley, A. S. Beasley, K. Berkwits, S. Boltax-Stern
(Child Study Center), H. D. Bornstein, Jr., K. A. Bradford, M. Browne, C. Canny,
R. Chessin, S. Danoff, M. Engel, J. Federico, J. B. Ferholt (Child Study Center),
J. D.
Ferholt, H. D. Fink, T. Flynn, J. Fong, R. Freedman, C. Goff, H. Goldenring,
F. L. Gruskay, J. Gundy, J. Hen, R. Herzlinger, A. Jamshidi, S. Levy, L. S.
McIntosh, M. Mercurio, S. Nallainathan, C. R. Palm, C. Randolph, R. Shelling,
E. L. Stone, F. Testa, R. Young
Assistant Clinical Professors
R. J. Anderson, M. Apkon, C. Aten, A. J. Avni-Singer, R. Berning, A. Bhargava,
R. M. Biondi, J. W. Blanton, Jr., N. Brown, J. Burger, C. Butler, D. Cheromcha,
J. Combs, N. Condulis, N. Czarkowski, P. Czuczka, N. Deleuchtenberg, S. Dibs,
C. Dorfman, D. Durante, G. Dworkin, A. R. Enriquez, T. Etkin, P. Fadakar, K.
Fearn, C. A. Fischbein, M. Galal, G. Germain, E. H. Gleich, A. J. Grant, G.
W. Grundy, J. Gruskay, R. Halperin, J. Hamilton (Social Work), J. Harper, R.
Hobbie, M. Hommel, M. Ikeda, W. D. Irving, R. Johnson, O. H. Lascano, L. Lasley,
S. Lavietes (Social Work), M. Lee, D. Lowell, C. Mann, E. Marmer, C. McEvoy,
A. Meyers, J. Morgan, C. Morrison, M. Pardi, A. Perez, S. Peterec, H. Pierce,
M. Robert, H. Romanowitz, M. Sanyal, R. Scalettar, N. Schamban, G. Schare, M.
Schneider, C. Scott, L. Semeraro, L. Shader, R. Shea, M. Siev, W. Silberberg,
M. Silverman, S. Spiesel, C. Stone, C. Summers, S. Theofanidis, S. Tsalbins,
J. Tuggle, S. Updegrove, J. Walterspiel, G. Wanerka, J. F. Wedgwood, N. Weinberger,
N. Weinstein, P. Weiss, R. F. Whelan, E. Wiesner, R. D. Windom, C. Wood, C.
Woods, J. Wynne
Clinical Instructors
R. Adamenko, P. Alvino, J. Anderson, A. Atton (Dermatology), S. Baum, L. Berlin,
M. Brochin, K. Burke, R. Carroll, J. Cersonsky, M. Dilorenzo, J. Dipisa, J.
Dobos, R. Dorr, D. Dreyfus, A. Driggers, P. O. Eagan, W. Flynn, D. Gallo-Van
Ess, B. Gardner, S. Gardner, G. J. Germano, M. A. Glenn, K. Goldberg, L. Gray,
D. Griffin, J. Harwin, A. Hoefer, F. Holmes, D. Idelson, T. V. Jackson, E. James,
L. Jayanthi, B. Jubelirer, S. Kayani, H. Kipperman, S. Leib, A. Liebling, D.
Lippi, R. Lockhart, C. Menzies, A. Mrozowski, N. Naran, C. Nicolosi (Social
Work), M. Pouliout, O. T. Rose, M. Shaw, S. Simon, E. R. Smith, M. P. Smith,
E. Springhorn, J. Stein, N. Stein, S. C. Stein, D. Thomas, D. Torres, M. P.
Uceda, M. Vincent, L. Waldman, J. Young
Postdoctoral Fellows and Associates
S. Bhaduri-McIntosh, V. Bhattacherjee, R. Bungiro, P. J. Chang, H. Chen, Q.
F. Chen, J. Delaney, M. Dodson, K. Dudley, J. Enciso, F. Esper, A. Esquibies,
R. Farahani, G. Fyfe, H. Hallaq, E. Hernandez, A. Hsiao, S. Husain, S. Jacob,
J. Khan, H. Klenoff, H. Kocinsky, M. Kim, S. Lakhani, I. Lazar, B. Lechner,
K. T. Lee, D. Listman, J. Moltedo, J. Nedrelow, N. Nikolaeva, I. O’Kelly,
R. Othman, C. Raskind, M. Riordan, J. Ryu, H. Schneider, M. Seli, Y. Senturias,
M. Sivasubramaniam, T. Shih, F. Thierfelder, H. Trubel, C. Turner, E. Vicencio,
L. X. Wang, R. Weiss, J. Zhang, P. Zhao, G. P. Zhou, S. Xia, Y. Y. Xia, S. Xiaolu,
J. Xue
Lecturers
C. Cook, K. Feiden, P. Killeen
Pediatrics 103, Third-Year Clerkship. The Pediatric Clerkship consists
of four major parts: three different clinical experiences and a core curriculum.
One clinical experience is a two-week ambulatory rotation in a primary care
setting. Another two-week rotation allows students to join a pediatric subspecialty
team or to work in the Pediatric Intensive Care Unit. The third clinical experience
consists of a four-week rotation on the inpatient service at the Children's
Hospital at Yale-New Haven or at Bridgeport Hospital. One afternoon each week
is devoted to pediatric grand rounds and teaching conferences in which the core
curriculum is presented. W. A. Andiman.
Pediatrics 104, Outpatient Clerkship. Students assume responsibility,
under supervision, for comprehensive care of children. They evaluate children
referred to the clinic with diagnostic problems. Special emphasis is placed
on problems related to the ambulatory patient. Senior students only. One student,
full time, for three weeks. P. L. McCarthy and staff.
Pediatrics 128, Hematology-Oncology. A survey of the normal and abnormal
hematology of infancy and childhood. Special emphasis on the diagnosis and management
of the common anemias, malignancies, and bleeding disorders of children. One
student, full time, for three or more weeks, throughout the academic year. G.
Plautz and staff.
Pediatrics 139, Pediatric Neurology. Students participate in the pediatric
neurology clinic and the learning disorders unit and see neurology patients
on the pediatric wards. Up to two students, full time, for three weeks, throughout
the academic year. L. R. Ment, E. Novotny, B. Shaywitz, S. Shaywitz, M. Engel,
S. Levy, F. Testa.
Pediatrics 143b/Surgery 136b, Pediatric Surgery. A general survey of
pediatric surgical problems based on illustrated case summaries and subject
presentation by students, with selected readings from the literature. Limited
to six students, first and last six weeks of spring term. Once weekly, time
to be arranged. J. H. Seashore, R. J. Touloukian.
Pediatrics 144, Clinical Clerkship in Pediatric Cardiology. Developmental
aspects of cardiovascular function as applied to infants and children in both
a clinical and a laboratory setting. Students are assigned to various members
of the pediatric cardiology staff. Emphasis on physical diagnosis, use of noninvasive
methods, and clinical physiologic correlates. Up to two students every four
weeks throughout the year. M. Brueckner, J. Fahey, A. H. Friedman, C. Snyder,
P. Bowers, G. Porter.
Pediatrics 146, Clinical Pediatric Infectious Diseases. Students participate
in daily consultation rounds, Pediatric AIDS Clinic, and pediatric infectious
diseases clinic. Students also participate in pediatric infectious disease rounds
by presenting the case studies of one or more inpatients whom they have examined
to a group of faculty and fellows. Rounds last approximately two hours (Thursday
afternoon). Emphasis is placed on correlation of the clinical problem and its
practical management with principles of infectious disease epidemiology and
clinical microbiology (bacteriology, virology, and parasitology). Limited to
two students per three- to six-week period throughout the academic year. W.
Andiman, R. Baltimore, M. Cappello, J. Kahn, J. McKinney, G. Miller, M. Vazquez.
Pediatrics 148, Pediatric Endocrinology and Metabolism. An extensive
exposure to clinical pediatric endocrinology, in particular problems of growth,
sexual development, thyroid disorders, and diabetes mellitus and other disorders
of carbohydrate metabolism. A full six-week elective includes three weekly general
endocrinology clinics, two weekly diabetes clinics, and a hyper lipidemia/obesity
clinic, and the inpatient service, generally concentrated in the Children's
Clinical Research Center. One student, full-time, six weeks, throughout the
academic year. S. Caprio, T. Carpenter, M. Genel, T. Monsod, S. Rivkees, W.
V. Tamborlane.
Pediatrics 152, Subinternship. Senior students serve as advanced clinical
clerks in order to gain experience in providing care to pediatric patients.
During the subinternship, students are directly responsible for the care of
their assigned patients, under the supervision of resident and attending physicians.
Subinternships are served for three-four week periods on any of the inpatient
divisions within the Department of Pediatrics at the Children's Hospital at
Yale-New Haven. N. J. Siegel and staff.
Pediatrics 153, Pediatric Gastroenterology/Hepatology. A general survey
of clinical pediatric gastroenterology and hepatology with particular emphasis
on inflammatory bowel disease, malabsorption, diarrheal disorders, nutrition,
and liver disease. The elective includes daily inpatient rounds, three weekly
clinics, and several weekly clinicopathologic conferences, as well as observation
of endoscopic procedures. One student, full-time, three or six weeks, throughout
the academic year. C. McEvoy, S. Moyer, T. Denson, W. Echevarria, S. Escalera.
Pediatrics 154, Pediatric Respiratory Medicine. During the elective,
students are exposed to a range of activities in the Section of Respiratory
Medicine. These include the evaluation of respiratory and pulmonary function
in a variety of disease conditions, and care of infants and children with respiratory
diseases such as asthma, cystic fibrosis, bronchopulmonary dysplasia, pneumonia,
aspiration syndromes, and obstructive sleep disorders. Emphasis is on physical
diagnosis. Rotations through the pulmonary function laboratory and the Children’s
Sleep Center. Laboratory experience can be arranged. Participation in seminars,
journal club, and patient rounds and clinics. Two students, every four weeks,
throughout the academic year. A. Bazzy-Asaad, M. Egan, G. G. Haddad, L. Kass,
R. Palazzo.
Pediatrics 155, Pediatric Emergency Medicine. Senior students have the
opportunity to evaluate and manage a broad range of acute pediatric illnesses
under direct attending supervision. Participation in daily teaching conferences,
“mock” codes, and clinical practice exercises is encouraged. Clinical
duties are distributed over five six-hour clinical shifts per week. Up to two
students every four weeks, throughout the academic year. A four-week rotation
is recommended. M. D. Baker and staff.
Pharmacology
Office: SHM B204, 785.4372
Professors
G. K. Aghajanian (Psychiatry), K. S. Anderson (Director of Medical Studies),
G. P. Beardsley (Pediatrics), H. R. Behrman (Obstetrics and Gynecology), B.
S. Bunney (Psychiatry), E. S. Canellakis (Emeritus), Y. C. Cheng, E. Chu (Internal
Medicine), J. R. Cooper (Emeritus), P. S. Dannies, R. S. Duman (Psychiatry),
B. E. Ehrlich, R. E. Handschumacher (Emeritus), R. B. Innis (Psychiatry), R.
Jahn (Adjunct), L. K. Kaczmarek, E. G. Moczydlowski, W. H. Prusoff (Emeritus),
J. M. Ritchie, S. C.
Rockwell (Therapeutic Radiology), R. H. Roth, Jr. (Psychiatry), G. Rudnick (Vice
Chair), A. C. Sartorelli, J. Schlessinger (Chair), W. Sessa (Director of Graduate
Studies), S. G. Waxman (Neurology)
Associate Professors
A. Gribkoff (Adjunct), R. Heimer (Epidemiology and Public Health), J. Howe,
R. Kalb (Neurology), E. Lolis, M. Picciotto (Psychiatry), G. Pizzorno (Internal
Medicine), J. Tallman (Psychiatry; Adjunct), T. Verdoorn (Adjunct)
Assistant Professors
A. Bennett, C. M. Crews (Molecular, Cellular, and Developmental Biology), M.
P. DiGiovanna (Internal Medicine)
Research Scientists
J. Liddil (Visiting), D. Stagg, Y.-L. Zhu (Visiting)
Associate Research Scientists
R. P. Baumann, Jr., S. Bian, M. Bordonaro, D. Cao, H. Gu, K. Ishiguro, D. Johnson,
F. Kilic, M.-C. Liu, M.-Z. Luo, N. Magoski, P. Penketh, A. Pivazyan, K. Shyam,
M. Stephan, B. White, Z. Zhang
Research Affiliates
H.-M. Chang, J. Feng, W. Hodnick, Z. Jiang, S.-H. Liu, C. Marlor, C. Pappas
Postdoctoral Fellows
A. Androutsellis-Theotokis, J. Cai, K. M. Chou, B. Degeve, D. Fulton, J.-P.
Gratton, K. Holtz, C. C. Hsieh, F. Johenning, P. Krishnan, W. Lam, D. L. Lazarova,
Y. Lee, K. J. Makati, J. Mei, S.-Y. Park, A. Rice, M. Sachsamanoglou, R. Scotland,
E. Thrower, C.-J. Wang, A. Yamaguchi, J. Yu, H. Zeng, S. Zoellner
Postdoctoral Associates
P. Bauer, A. Bhattacharjee, J. P. Bingham, M. Deller, P. Flannary, W. Joiner,
S. Kolli, Z. Li, J.-Y. Li0u, E. Murakami, Y. Sato, A. Sau, Y. Zhang, Y.-W. Zhang
Lecturers
J. G. Collins (Anesthesiology), L. M. Dembry (Internal Medicine), G. E. Gardiner,
M. Hodsdon (Laboratory Medicine), R. J. Levine (Internal Medicine), J. M. Pawelek
(Dermatology), A. Scriabine
Pharmacology 502a/b, Seminar in Pharmacology. A seminar given by a department
faculty member on his or her area of interest to teach students how to critically
evaluate papers and to improve the ability of students to give oral presentations.
Pharmacology 504a, Pharmacology I: Maintaining and Restoring Homeostasis.
Lectures cover drug-receptor interactions, control of messenger systems and
channels, and regulation of physiological systems. P. Dannies and staff.
Pharmacology 504b, Pharmacology II: Interfering Selectively. Lectures
cover antibiotics, immunotherapy, and chemotherapy. P. Dannies and staff.
Pharmacology 506a/b, Methods in Pharmacological Research (Rotations).
Students work in laboratories of faculty of their choice. The term in each laboratory
is one term. Hours to be arranged. W. Sessa.
Pharmacology 508b, Neuropharmacology. An intensive examination of current
understanding of the sites and mechanisms involved in drug action on single
nerve cells and on the brain. Emphasis on basic functions and illustrative examples
of their disturbance by drugs. J. M. Ritchie.
Pharmacology 509b/Psychiatry 175b, Neurobiology of Drug Addiction. Overview
of knowledge of the mechanisms underlying drug addiction at the molecular, cellular,
and neural systems levels. Staff.
Pharmacology 510b, Life Science Business. Exploration of where the life
sciences intersect with finance and the law from a variety of perspectives including
those of industry, academia, and the communications media. G. E. Gardiner.
Pharmacology 518b, Current Topics in Cancer and Viral Therapy. Y. C.
Cheng, E. Lolis.
Pharmacology 520a, Principles of Research Methodologies: Methods Behind
the Madness. This course is designed for first-year students and illustrates
basic principles of contemporary techniques commonly used in many research laboratories.
The class is taught by faculty and senior students in the Department of Pharmacology.
The class meets for two hours weekly. Grades are distributed based on class
attendance, participation, and take-home questions that are administered for
each block of lectures. W. C. Sessa, P. Dannies.
Pharmacology 522a, Neuroimaging in Neuropsychiatry. Neuroimaging methodologies
including Positron Emission Tomography (PET), Single Photon Emission Computed
Tomography (SPECT), Magnetic Resonance Imaging (MRI), functional Magnetic Resonance
Imaging (fMRI), and Magnetic Resonance Spectroscopy (MRS) are rapidly evolving
tools used to study the living human brain. Neuroimaging has unprecedented implications
for routine clinical diagnosis, for assessment of drug efficacy, for determination
of psychotropic drug occupancy, and for the study of pathophysiological mechanisms
underlying neurologic and psychiatric disorders. This course is designed to
provide an overview of the theory and current state of development of the different
neuroimaging modalities and their application to research in neurologic and
psychiatric disorders. J. K. Staley (organizer).
Psychiatry
Office: GB 618, 785.2117
Professors
G. K. Aghajanian, S. J. Blatt, M. B. Bowers, Jr., B. S. Bunney (Chair), K. Carroll,
R. S. Duman, M. Edelson (Emeritus), P. L. Errera (Emeritus), S. Fleck (Emeritus),
P. S. Goldman-Rakic (Neurobiology), E. Griffith, G. Heninger, R. B. Innis, S.
C. Jacobs, P. Jatlow (Laboratory Medicine), K. K. Kidd (Genetics), R. A. King
(Child Study Center), T. R. Kosten, J. H. Krystal, M. Lewis (Child Study Center),
G. F. Mahl (Emeritus), J. W. Mason (Emeritus), C. M. Mazure,T. H. McGlashan,
D. Musto (Child Study Center), A. C. Nairn, J. C. Nelson, S. S. O’Malley,
D. M. Quinlan, F. Redlich (Emeritus), D. E. Redmond, M. Reiser (Emeritus), R.
Rosenheck, R. H. Roth, Jr., B. J. Rounsaville, R. Schottenfeld, J. E. Schowalter
(Child Study Center), M. Sheard (Emeritus), W. H. Sledge, D. L. Snow, A. J.
Solnit (Child Study Center; Emeritus), S. Southwick, J. S. Strauss (Emeritus),
F. R. Volkmar (Child Study Center), H. V. Zonana
Associate Professors
M. Alreja, S. K. Avants, S. A. Ball, R. Belitsky, M. Bell, N. Boutros, C. Bradberry,
N. L. Cooney, J. Cubells, L. Davidson, E. Diaz, D. C. D’Souza, J. E. Gelernter,
E. Giller (Adjunct), A. Goddard, C. Grilo, K. Hawkins, R. E. Hoffman, M. A.
Hoge, R. D. Kerns, R. Malison, S. Martino, B. Moghaddam, C. A. Morgan III, D.
Oren, H. R. Pearsall, I. L. Petrakis, M. Picciotto, S. Powsner, H. Prigerson,
M. I. Rosen, M. J. Sernyak, Jr., W. Shi, K. J. Sikkema, R. Sinha, J. L. Steiner,
J. Tallman (Adjunct), J. Taylor, J. Tebes, C. Van Dyck, B. Wexler, S. W. Woods,
K. A. Yonkers
Assistant Professors
W. Abi-Saab (Adjunct), L. Anez-Nava, C. Baker, R. Berman (Adjunct), H. Blumberg,
D. Brunner (Adjunct), D. Budimirovich, M. Chawarski, J. Chen, M. Chinman, M.
Desai, R. A. Desai, B. Druss, C. Easton, C. N. Epperson, M. Fujita, T. George,
G. Gonzalez-Haddad, L. Jacobsen, M. Jean-Baptiste, W. Kasprow, J. Kaufman, J.
Kaufman, T. Kosten, S. Krishnan-Sarin, S. D. Kruger, D. Leslie, D. Lipschitz,
S. Madonick, G. Marek, A. Martin (Child Study Center), R. Masheb, G. Mason,
D. Mathalon, S. McKee, T. McMahon, M. V. Pantalon, J. Poling, M. Potenza, A.
Preda, A. Rasmusson, C. Ripple, G. Sanacora, C. Sanislow, G. Sirugo (Adjunct),
J. Staley, D. Stayner, T. Styron, D. Vojvoda, J. Zell
Instructors
S. Khan, G. Richardson
Senior Research Scientists
D. V. Cicchetti (Child Study Center), J. D. Elsworth
Research Scientists
R. Baldwin, K. Behar, A. F. Fontana, A. Margolin, A. Oliveto-Beaudoin, M. K.
Pruett, G. Tamagnan
Associate Research Scientists
S. Axelrod, R. Beech, I. Cavus, M. Copenhaver, J. Cramer, K. Crone, K. D’Avanzo,
L. Fenton, D. Gordon, T. Greig, G. Insabella, A. Jaffe, J. Jentsch, M. Jofre-Bonet,
B. Kloos, A. Kugaya, D. Lewis, W. Lynch, K. S. Marcus, D. Martin, C. Milligan,
B. Morrow, M. Paris, R. W. Robin, J. Saksa, B. Scanley, N. Suchman, S. Swan,
D. Tate, L. Warburton, N. Ward, M. Wu
Research Affiliates
J. Auerbach, J. Bombace, G. J. Bryson, L. Frisman, D. Hoffman, S. Luthar, M.
Miserendino, C. L. Seibyl, E. Triffleman
Clinical Professors
R. Arnstein (Emeritus), T. W. Downey (Child Study Center), G. H. Flamm, C. W.
Gardner, Jr., D. G. Greenfeld, S. A. Leavy, R. Newman (Emeritus), E. Prelinger,
L. W. Reiser, C. E. Riordan, H. L. Ruben, H. S. Sacks (Child Study Center),
L. D. Siggins
Associate Clinical Professors
J. Allison, V. Altshul, R. Balsam, D. Berg, D. Bialos, S. Boltax-Stern (Child
Study Center), E. Brett, D. Carlson, J. Ciarcia, G. Cohn, R. Cooper, J. De Figueiredo,
J. B. Ferholt (Child Study Center), J. Geller, R. L. Goettsche, K. Grady, L.
Harkness, J. E. Henisz, R. J. Hoffnung, D. Johnson, J. A. Kleeman, R. Klein,
C. C. Kovel, J. Laffal, D. Laub, I. Levine, K. O. Liebmann, J. Lustman, J. B.
McKee, L. J. Micheels, D. C. Moore, R. Ostroff, D. Perlick, R. Peters, Jr.,
J. Phillips, S. H. Phillips, S. G. Possick, R. Rohrbaugh, M. Rowe, M. A. Rubenstein,
E. R. Ryan, R. Sallick, J. Schnitt, S. J. Schreiber, A. H. Schwartz (Child Study
Center), A. Siegal, E. W. Snyder, R. Stern, T. Stewart, J. Young
Assistant Clinical Professors
A. Adis, R. Ahrens, A. Almai, P. Amble, C. Atkins, S. Atkins, A. Balter, M.
Baranoski, L. C. Barr, M. Barrios, E. Bastone, A. Bauer, B. Becker, R. Behrends,
C. Bemis, S. Bender, D. Bendor, E. Berger, T. Bergherr, S. A. Bers, H. C. Blue,
D. Boltas, T. Brown, A. Brownlow, B. Burns, A. Cappiello, C. Carlson, R. Casey,
L. I. Chaikovsky, J. Check, C. C. Chi, J. Chilakamarri, C. Chiles, A. Cinquanta,
J. T. Collins (Child Study Center), C. Corcoran, V. Coric, C. Cottrol, G. H.
Davis, K. Degen, M. Di Tomasso, C. Doebrick, N. Donegan, M. T. Dreyfus, J. Erdos,
A. Evans, C. Farren, D. Fehon, M. Felts, J. Fickes, L. Fierman, S. Finkelstein,
G. J. Firman, P. A. Fountain, P. Fox, D. Fried, R. Geller, R. Giebisch, E. E.
Glass, T. Glinberg, N. R. Gluck, C. T. Goldberg, P. B. Goldblatt, L. Goldstein,
M. Goldstein, K. Gonsi, C. Gonzalez, L. Gonzalez, G. H. Gordon (Internal Medicine),
C. Gottschalk, C. Greene, K. Grimmell, M. Groner, E. Grottole, C. S. Grove,
L. Grunebaum, F. A. Hameedi, E. Hart, S. Hill, W. L. Hill, M. Hillbrand, O.
Hills, S. Horowitz, S. Houlding, J. Jackson, D. D. Jacobson, H. G. Jarecki,
C. Jean, A. Kaner, A. Kaufman, K. Kennedy, K. Kiehl, R. G. King, P. Kirwin,
B. Klink, B. Knox, F. E. Koerner, J. L. Kurt, M. M. Kurtz, A. Lamba, H. Lankenau,
D. Lapaglia, J. H. Lederer, S. Lee, N. E. Legow, L. Levenson, J. M. Levine,
S. Lewis, E. Littman, H. Lizcano, D. London, K. Long, H. Lubin, M. Mandelkern,
B. Marcus, L. Martel, C. Martinez, C. Maynard, S. M. McCants, R. McCleary, B.
B. McConnell, B. Meandzija, A. Meisler, A. Miano, S. J. Migdole, H. Miller,
T. Miller, E. Millman, R. M. Milstein, F. Minichiello, V. Morrow, F. C. Mueller,P.
V. Mulinski, J. Murray, E. Nasper, M. Newell, J. Nields, M. Norko, D. Nudel,
K. Nuro, A. M. Oberkirch, M. S. Okasha, N. Olson, C. Opsahl, A. Oren, B. Orrok,
R. Ownbey, C. Palman, A. Papsun, C. Pearson, L. Perone, W. Phillips, G. Plotke,
M. L. Prevey, G. Racusin, J. Rakfeldt, I. Rathbone, A. Resnick, L. Robertson,
J. Robinson, C. T. Rotenberg, M. Roy, R. Rubin, C. Russell, D. S. Russell, J.
A. Sabbatino, J. K. Sadowitz, K. Salisbury, C. Sanders, L. Sanfilippo, C. Santangelo,
M. Savage, R. Sbriglio, J. Schechter, R. Schreibman, K. D. Schultz, J. Scott,
Jr., S. R. Segall, D. Sholomskas, S. E. Silverman, S. Sreenivasan, W. A. Stewart,
M. Stitelman, G. E. Sturges, R. Sussman, A. B. Tanagho, A. Tessler, B. Tobin,
P. Torop, L. Trevisan, M. Tupper, S. H. Tworkowski, D. Wallington, T. Ward-Mckinlay,
S. D. Wayne, J. M. P. Wexler, R. S. White, J. Williams, C. Wiseman, B. Zigun,
S. Zimmerman, Z. Zimolo
Clinical Instructors
T. Alford, M. Bailey, J. Beauvais, E. Becker-Dunn, S. Brown, V. Coggshall, J.
F. Collins, I. M. Dineen, D. Fisk, S. Fitzpatrick, D. Flanigan, J. Frey, C.
Grazia, M. C. Grenough, S. Hegde-Rodrigues, P. Herbert, D. Hunt (Social Work),
D. Klein, W. Levy-Massarani, P. Mohrer, M. Nicholas, C. Nicou, R. G. Prabhulal,
J. N. Rascati, S. Rathi, J. Robbins, H. S. Sackler, K. Tracey, A. Vamvakas,
M. Vollmar
Lecturers
J. D. Alvaro, L. Ameen, B. Backus, S. Berman, D. Berv, K. Berv, E. Bialek, A.
Blank, Jr., W. Boutelle, L. Brauer, J. Bristol, D. Ciancimino, E. Coley, C.
Conrad, H. Crabbe, D. Davis, A. Demac, C. Duman, A. Dworetz, W. G. Faraclas,
C. Feldman, M. L. Glucksman, S. Goodson, J. Gordon, G. Greenberg, E. G. Halstead,
M. Kalacznik, B. Klein, A. Koleszar, R. Kravitz, A. Labruzza, L. Lager, H. Leigh,
C. Lenoci, R. Lenoci, M. Levine, N. Lifton, R. Makover, K. Marcus, A. Mares,
J. R. Merikangas, J. H. Meyer, M. Mitchell, I. Moses, R. L. Munich, S. L. Nichols,
J. I. Novick, K. Owen, R. Phillips, S. A. Quinlan, M. Rego, W. Reich, B. G.
Rifkin, D. Rightmer, A. Rodriguez, J. A. Roth, E. B. Rubin, S. L. Satel, D.
Schwartz, A. Sholomskas, G. H. Sirkin, R. Z. Solomon, W. Spear, C. Tesluk, P.
Thomas, M. Vythilingam, E. Weiss, A. Whitney
The Department of Psychiatry teaches in both preclinical and clinical years.
The pre-clinical course is a study of medical behavioral science, rather than
an introduction to clinical psychiatry. Specific clinical skills, such as interviewing
and the recognition and management of psychiatric syndromes, are taught later
in the curriculum and especially during the required clinical clerkship in Psychiatry.
Electives are available for students with special interest in selected areas.
All advanced clinical electives are numbered in the 200s. The required core
clinical clerkship (Psychiatry 106) is a prerequisite for enrollment in any
of these advanced clinical electives; an advanced clinical elective may not
be taken instead of the required core clinical clerkship. Please note: All
students signing up for a seminar elective must also register with the Medical
Student Education Office, Department of Psychiatry, 785.2089 (pending approval
of the instructor).
Psychiatry 101a, Psychological Aspects of Medical Practice. This segment
of the Doctor-Patient Encounter course focuses on the experience of illness-how
people react to and cope with illness. The various psychosocial factors and
psychological defenses which impact on the experience of illness, such as age,
gender, social supports, socioeconomic status, and coping style, are examined.
There is an emphasis on the patient interview and techniques for eliciting the
patient's story in an empathic and effective manner. The format includes patient
interviews followed by small-group discussion. R. Belitsky and Department of
Psychiatry faculty.
Psychiatry 101b, Biological Basis of Behavior. Lectures are integrated
with the Neurology course, and include principles and neural mechanisms of learning
and memory; neural systems involved in fear and anxiety; neural systems involved
in reward and drug addiction; neural systems involved in stress; and neural
systems involved in attention. Following each lecture, a psychiatrist interviews
patients diagnosed to have either obsessive-compulsive disorder, panic disorder,
cocaine abuse, post-traumatic stress disorder, or schizophrenia. These 1.5-hour
clinical presentations, which include time for questions, link psychiatric symptoms
to the neural mechanisms discussed in the lecture on that day. 2.5 hours per
week. Department of Psychiatry faculty.
Psychiatry 106, Core Clinical Clerkship. Skills and knowledge needed
for the general practice of medicine are acquired in a clinical psychiatric
setting. These include the ability to conduct a competent screening interview;
to identify symptoms of a psychiatric or substance abuse disorder; to perform
a complete mental status examination of a patient who is emotionally disturbed
or mentally ill; to make a differential diagnosis, and to plan for further evaluation
and tests that would be useful in deciding among various diagnostic possibilities;
to make recommendations for initial treatment or referral; to assess whether
or not dangers to or from a patient exist; and to understand indications and
procedures for lawful involuntary commitment of a patient to a mental hospital
for treatment. R. Rohrbaugh and Department of Psychiatry faculty.
Psychiatry 107/Obstetrics and Gynecology 104, Shared Clerkship in Medical
Psychiatry. This clerkship, administered jointly with the Department of
Obstetrics and Gynecology, is designed to provide students with an understanding
of the presentation of psychiatric illness in patients with co-morbid medical
disorders. Emphasis is placed on screening interviews, including mental status
examination; identification of symptoms; and differential diagnosis and initial
treatment recommendations in patients with co-morbid and psychiatric illness.
Special emphasis is placed on evaluation of psychiatric emergencies and competency
to make informed medical decisions. R. Rohrbaugh and Department of Psychiatry
faculty.
Psychiatry 203, Subinternship in Hospital Psychiatry, Inpatient Division,
Connecticut Mental Health Center. Intensive work with inpatients who suffer
from major psychiatric disorders with or without substance abuse. Emphasis is
on assessment, acute treatment, and arrangement of continuing care in the community.
The clerk functions as an integral member of a multidisciplinary treatment team.
Clinical research participation is encouraged. Opportunities available to explore
special areas of interest (e.g., forensics, psychopharmacology, administrative)
with Connecticut Mental Health Center faculty. The elective is given on the
inpatient service, CMHC. Scheduled throughout the year during regular clerkship
rotations for a minimum of four weeks. Prerequisite: Psychiatry 106. Maximum
registration: two students. R. Pearsall, S. Jacobs, J. Zell, S. Nichols, M.
Jean-Baptiste, and staff. To enroll in this subinternship, please contact R.
Rohrbaugh.
Psychiatry 205, Subinternship in Medical Psychiatry, Yale-New Haven Hospital,
2039 Clinic Building. This is an advanced clinical elective for third- and
fourth-year students who have a particular interest in the psychiatric disorders
that can occur in medical-surgical patients. The staff has special interests
in differential diagnosis of medical vs. psychiatric illness, in psychopharmacology,
and in computer applications in psychiatry. Each student works up patients in
parallel with advanced residents in inpatient and emergency department settings.
Teaching occurs on daily walk rounds. Scheduled throughout the year during regular
clerkship rotations (except July and August) for a minimum of four to six weeks.
(NOTE: Fourth-year students will be given preference. ) Prerequisite: Psychiatry
106. Maximum registration: one student per rotation. P. Desan, T. Stewart, S.
Powsner, W. H. Sledge, and staff. To enroll in this subinternship, please contact
R. Rohrbaugh.
Psychiatry 206, Advanced Clinical Elective in Law and Psychiatry. This
clerkship program affords opportunities for third- and fourth-year medical students
to observe and participate in "competency to stand trial" evaluations
with a clinical team that makes these assessments at the New Haven Correctional
Center. In addition, they may attend Law School classes with students who represent
psychiatric patients, observe civil commitment procedures, attend probate court
hearings, as well as the criminal proceedings in local New Haven Superior Courts.
Students attend work seminars where case evaluations and write-ups are discussed
and prepared, and read appropriate legal cases and psychiatric literature. Students
may be able to participate in parts of evaluations of insanity defense, custody
determination, and other forensic issues. They attend the Law and Psychiatry
Seminar during their rotation. Scheduled throughout the year (except August)
during regular clerkship rotations for a minimum of four weeks. Prerequisite:
Psychiatry 106. Maximum registration: two students. H. Zonana. To enroll in
this advanced clinical elective, please contact R. Rohrbaugh.
Psychiatry 208, Subinternship in Consultation-Liaison Psychiatry at the
Veterans Administration Connecticut Health Care System (VACHS), West Haven,
Connecticut. The Consultation-Liaison Service at the VACHS West Haven provides
consultation to acute medical and surgical units, specialized rehabilitation
units, and outpatient primary care clinics. Students participate in the management
of patients with close supervision from attending staff. The goals of the rotation
are (1) to increase skill in conducting a psychiatric interview which maximizes
the collection of pertinent clinical data; (2) to use the data collected in
formulating and implementing treatment plans emphasizing the interplay of biological
and psychological factors in the patients' presentation; (3) to experience the
satisfaction of caring for patients with complex medical and psychiatric illness.
Scheduled throughout the year (except July and August) for a minimum of four
weeks. Open to third- and fourth-year medical students. Prerequisite: Psychiatry
106. Maximum registration: one student per rotation. C. Chiles and staff. To
enroll in this subinternship, please contact R. Rohrbaugh.
Psychiatry 210, Subinternship in Hospital Psychiatry, Inpatient Division,
Yale- New Haven Psychiatric Hospital. Intensive work with patients who suffer
from major psychiatric disorders and range in age from college students to middle
age. Emphasis is on assessment, acute treatment, and arrangement of post-discharge
follow-up care in the community. The subintern is an advanced clerk functioning
as a member of the multidisciplinary treatment team, taking on primary clinician
and psychiatric/medical responsibilities for patients under the supervision
of senior clinicians. The elective is given on the inpatient service at Y-NHPH;
clinical research and outpatient involvement may be options. This subinternship
is available throughout the year, during regular clerkship rotations for a minimum
of four weeks. Prerequisite: Psychiatry 106. Maximum registration: one student
per rotation. R. M. Milstein, M. Bowers, C. Mazure, and staff. To enroll in
this subinternship, please contact R. Rohrbaugh.
Psychiatry 211, Subinternship in Clinical Neuroscience, Clinical Neuroscience
Research Unit Inpatient Division. This clerkship offers senior medical students
the opportunity to work closely with a variety of patients who are hospitalized
during their participation and treatment in research protocols. The Clinical
Neuroscience Research Unit (CNRU) is a thirteen-bed inpatient ward with associated
outpatient clinics and basic science laboratories on the third floor of the
Connecticut Mental Health Center (CMHC). Supervised implementation of novel
psychopharmacology, exposure to multiple aspects of clinical and basic science
research, and in-depth experience with individual and group psychotherapies
are educational aspects of this elective. Patients' diagnostic categories include
depression, obsessive-compulsive disorder, schizophrenia, cocaine abuse, and
substance abuse. Scheduled throughout the year for a minimum of four weeks.
Prerequisites: Psychiatry 101 and 106. Maximum registration: one student per
rotation. R. Malison, V. Coric, and staff. To enroll in this subinternship,
please contact R. Rohrbaugh.
Psychiatry 212, Subinternship in Post-Traumatic Stress Disorder, National
Center for PTSD at the Veterans Administration Connecticut Health Care System
(VACHS), West Haven, Connecticut. This clerkship offers senior medical students
the opportunity to participate in the research and clinical activities of the
National Center for PTSD. This experience includes exposure to a research program
that has taken a national leadership role in identifying the effects of severe
psychological trauma on brain structure and function using a variety of neuropharmacological,
neuropsychological, and brain imaging modalities. The patients under study include
men and women who have been exposed to physical and sexual abuse and the trauma
associated with combat. Scheduled throughout the year for a minimum of four
weeks. Prerequisite: Psychiatry 106. Maximum registration: two students per
rotation. S. Southwick and staff. To enroll in this subinternship, please contact
R. Rohrbaugh.
Psychiatry 214, Subinternship in Psychotic Disorders at G8W and the Schizophrenia
Research Clinic at the Veterans Affairs Connecticut Health Care System (VACHS)
in West Haven, the Clinical Neuroscience Research Unit and the Psychopharmacology
Intervention Program at the Connecticut Mental Health Center, the Community
Care Center in West Haven. This subinternship is designed to provide an
integrative exposure to the interface of psychopharmacology and psychosocial
treatments for chronic psychotic disorders. Each individual requesting a subinternship
is asked to outline his or her interest in psychotic disorders. Based on this
information, a faculty mentor is assigned and a clinical program prepared that
provides greater depth in the relevant areas. An effort is made to provide exposure
to both hospital- and community-based treatments as well as clinical neuroscience
advances. Within all treatment settings, subinterns have closely supervised
direct clinical contact with patients. Subinterns are invited to attend academic
conferences within the Department of Psychiatry focused on clinical and neuroscience
issues relevant to psychosis. The goals of the rotation are (1) to expose the
subintern to established and experimental medication treatments for psychotic
disorders, particularly schizophrenia; (2) to expose the subintern to rehabilitative
approaches to schizophrenia; (3) to expose the subintern to community-based
treatments for chronic mental illness. Scheduled throughout the year for a period
of six to eight weeks. Prerequisite: Psychiatry 106. Maximum registration: two
students per rotation. C. D'Souza, M. Bell, J. Cubells, L. Davidson, L. Harkness,
S. Kruger, J. Krystal, and staff. To enroll in this subinternship, please contact
R. Rohrbaugh.
Psychiatry 297/Internal Medicine 197/Obstetrics and Gynecology 197, Multidisciplinary
Approach to Women's Health. This course, run by the departments of Internal
Medicine, Obstetrics and Gynecology, and Psychiatry, offers a multidisciplinary
approach to gender-specific health issues across the life span of women. Inherent
in the model is a focus on the total health of each patient. Two days per week
are devoted to independent study and twelve didactic case-based sessions on
topics including domestic violence, contraception, medical complications of
pregnancy, breast cancer, menopause, osteoporosis, cardiovascular disease, and
epidemiology and prevention in the health of women. Most didactic sessions are
led by several experts on the topic, each representing his or her own discipline.
Clinical sessions are preceded by an intensive review of the breast and pelvic
exam led by professional teaching models. Three days per week are devoted to
clinical experiences that allow students to assess women patients within primary
care, gynecology, and psychiatric settings, as well as to be involved in specialty
areas such as pregnancy termination (optional), breast clinic, cardiac wellness,
mammography, and bone density. This course meets the requirements for the Primary
Care Clerkship or can be taken as an elective. Not offered every month. Open
on a first-come first-served or a lottery basis. K. P. White (Internal Medicine),
E. E. Jones (Obstetrics and Gynecology), R. M. Rohrbaugh (Psychiatry).
Psychiatry 325/Child Study 325, Child Psychiatry Elective, Yale Child Study
Center. The aim of this elective is to provide the student with an intensive
experience in infant, child, and adolescent psychiatry. The curriculum includes
assessments of normal development and psychopathology in childhood, treatment
methods, and research in major disorders of childhood. The elective takes advantage
of the wide range of ongoing seminars, conferences, and clinical services in
place at the Child Study Center. Teaching methods include seminars, conferences,
field observations, ward rounds, and practica selected by the student following
consultation with the director of medical studies, Child Study Center. Open
to fourth-year students (not available during July and August). M. Lewis, J.
Woolston, and staff. To enroll in this advanced clinical elective, please contact
M. Lewis directly at 785.2546.
Surgery
Office: FMB 102, 785.2697
Professors
L. M. Bartoshuk (Otolaryngology), G. P. Basadonna (Transplantation), M. Centrella
(Plastic), J. W. Cole (Gastroenterology; Emeritus), E. Crelin (Anatomy; Emeritus),
S. J. Dudrick (Co-terminus with Bridgeport Hospital; Gastroenterology), J. A.
Elefteriades (Cardiothoracic), W. W. Glenn (Cardiothoracic; Emeritus), M. G.
Glickman (Urology; Diagnostic Radiology; Emeritus), B. G. Green (Co-terminus
with Pearce Laboratory; Otolaryngology), R. J. Gusberg (Director of Medical
Studies; Vascular), G. L. Hammond (Cardiothoracic), B. K. Kinder (Oncology),
J. A. Kirchner (Otolaryngology; Emeritus), G. S. Kopf (Cardiothoracic), J. F.
Kveton (Otolaryngology), S. B. Leder (Otolaryngology), D. J. Leffell (Dermatology),
G. E. Lindskog (Cardiothoracic; Emeritus), A. Lofqvist (Adjunct; Otolaryngology),
M. I. Lorber (Transplantation), B. Lytton (Urology; Emeritus), L. M. Manuelidis
(Neuropathology), C. F. McKhann (Oncology; Emeritus), I. M. Modlin (Gastroenterology),
J. A. Persing (Plastic), L. K. Pickett (Gastroenterology; Pediatrics; Emeritus),
R. Rabinovici (Trauma & Surgical Critical Care), S. H. Rosenbaum (Trauma
& Surgical Critical Care; Anesthesiology), A. T. Rosenfield (Urology; Diagnostic
Radiology), P. E. Rubin (Adjunct; Otolaryngology), J. Santos-Sacchi (Otolaryngology),
C. T. Sasaki (Otolaryngology), R. Satava (Gastroenterology), I. R. Schwartz
(Otolaryngology), J. H. Seashore (Pediatrics), Y. H. Son (Otolaryngology; Therapeutic
Radiology), B. E. Sumpio (Vascular), K. Taylor (Vascular; Diagnostic Radiology),
R. J. Touloukian (Pediatrics), R. Udelsman (Chair; Oncology and Endocrinology),
R. M. Weiss (Urology), H. K. Wright (Gastroenterology; Emeritus)
Associate Professors
J. J. Abrahams (Otolaryngology; Diagnostic Radiology), K. R. Anderson (Urology),
M. S. Bogucki (Emergency Medicine), J. W. Colberg (Urology), D. C. Cone (Emergency
Medicine), D. L. Cooper (Otolaryngology; Internal Medicine), L. C. Degutis (Emergency
Medicine), G. D’Onofrio (Emergency Medicine), H. Foster (Urology), H. L.
Frankel (Trauma & Surgical Critical Care), V. Gahtan (Vascular), J. P. Geibel
(Gastroenterology), T. L. McCarthy (Plastic), L. J. Rizzolo (Anatomy; Ophthalmology
and Visual Science), W. Rosenblatt (Otolaryngology; Anesthesiology), R. A. Rosenthal
(Oncology; Chief, VA), D. Ross (Otolaryngology), J. C. Rosser, Jr. (Gastroenterology),
R. R. Salem (Oncology), J. A. Schriver (Emergency Medicine), N. E. Seymour (Gastroenterology),
W. B. Stewart (Anatomy), G. Tellides (Cardiothoracic), J. G. Thomson (Plastic)
Assistant Professors
J. C. Alex (Otolaryngology), S. M. Bowers (Emergency Medicine), P. A. Brewer
(Emergency Medicine), A. Dardik (Vascular), A. L. Friedman (Transplantation),
L. Geiselhart (Transplantation), R. S. Jawa (Trauma & Surgical Critical
Care), S. W. Jolin (Emergency Medicine), K. J. Jubanyik-Barber (Emergency Medicine),
J. S. Leung (Emergency Medicine), M. A. McKee (Pediatrics), E. P. Monico (Emergency
Medicine), H. C. Moscovitz (Emergency Medicine), D. Narayan (Plastic), A. Poma
(Emergency Medicine), J. A. Razzak (Emergency Medicine), S. Roman (Oncology),
J. H. Shin (Plastic), M. Tandon (Trauma & Surgical Critical Care), M. Thanassi
(Emergency Medicine), A. Weihl (Emergency Medicine), R. Whinney (Trauma &
Surgical Critical Care), J. Yang (Trauma & Surgical Critical Care)
Instructors
C. J. Lovoulos (Cardiothoracic), G. Tolis (Cardiothoracic)
Senior Research Scientist
J. Latifpour (Urology)
Associate Research Scientists
S. Condos (Gross Anatomy), N. C. Kirkiles-Smith (Cardiothoracic), W. Li (Vascular),
C. Rahner (Gross Anatomy), Y. Wang (Cardiothoracic)
Research Affiliate
P. Biancani (Urology)
Clinical Professors
S. Ariyan (Plastic; Otolaryngology), M. S. Arons (Plastic), J. E. Fenn (Gastroenterology),
W. D. Johnston (Dental), D. W. Kohn (Dental; Pediatrics), S. B. Nuland (Gastroenterology),
R. B. Reinhold (Gastroenterology), R. S. Stahl (Plastic), E. Yanagisawa (Otolaryngology)
Associate Clinical Professors
N. A. Atweh (Trauma), M. S. Beinfield (Gastroenterology), Z. N. Chicarilli (Plastic),
J. M. Dowaliby (Otolaryngology), R. C. Fazio (Dental), A. R. Frankel (Dental),
A. J. Graham (Gastroenterology), H. L. Horton (Dental), R. K. Houlihan (Gastroenterology),
J. P. Kelly (Dental), K. Koral (Dental), K.-J. Lee (Otolaryngology), R. Lena
(Urology), W. B. McCullough (Gastroenterology), N. M. Passarelli (Gastroenterology),
J. M. Serling (Dental), L. W. Skope (Dental), S. A. Stein (Gastroenterology),
H. Stern (Cardiothoracic), A. L. Toole (Cardiothoracic), B. S. Weisbart (Dental)
Assistant Clinical Professors
H. Abrams (Gastroenterology), M. A. Bank (Trauma & Surgical Critical Care),
P. A. Barcewicz (Gastroenterology), M. Baron (Dental), A. Baskin (Urology),
T. P. Bell (Trauma & Surgical Critical Care), J. D. Berns (Dental), C. J.
Boreyko (Emergency Medicine), G. Bosker (Emergency Medicine), K. Bradley (Emergency
Medicine), J. M. Brogden (Gastroenterology), P. H. Cain (Dental), H. Cedarbaum
(Dental), B. Y. Cha (Dental), K. A. Ciardiello (Gastroenterology), D. G. Cloutier
(Dental), M. L. D’Aiuto (Trauma & Surgical Critical Care), R. J. Dean
(Urology), R. H. Delfini (Dental), R. W. DeNatale (Vascular), M. L. Dewar (Cardiothoracic),
A. T. Dioguardi (Dental), T. G. Duplinsky (Dental), J. Federico (Cardiothoracic),
S. V. Flagg (Plastic), J. M. Flynn (Emergency Medicine), A. R. French (Emergency
Medicine), S. I. Friedman (Otolaryngology), S. Fusi (Plastic), R. Garvey (Gastroenterology),
E. B. Gaynor (Otolaryngology), A. R. Goldstein (Dental), R. T. Golia (Dental),
L. G. Graff (Emergency Medicine), R. D. Grossman (Dental), J. Henley (Otolaryngology),
J. R. Hernandez (Otolaryngology), R. H. Hirokawa (Otolaryngology), G. E. Horblitt
(Dental), N. R. Horowitz (Oncology), J. A. Huttner (Dental), M. E. Ivy (Trauma
& Surgical Critical Care), R. B. Kaplan (Dental), D. E. Karas (Otolaryngology;
Pediatrics), G. J. Katigbak (Emergency Medicine), D. B. Keck (Dental), J. C.
Kirchner (Otolaryngology), P. A. Kraus (Urology), P. E. Krochmal (Emergency
Medicine), J. W. Kunkel (Emergency Medicine), D. Kusovitsky (Dental), E. M.
Kwasnik (Gastroenterology), W. Kwass (Vascular), H. A. Laffaye (Gastroenterology),
T. E. Lamonte (Emergency Medicine), S. B. Levine (Otolaryngology), D. Lin (Emergency
Medicine), G. Longstreth (Gastroenterology), R. A. Lowlicht (Otolaryngology),
J. Maisel (Emergency Medicine), M. Margolies (Dental), G. E. Mombello (Plastic),
D. J. Muller (Dental), S. H. Natkin (Dental), H. Newman (Urology), G. R. Nicastri
(Trauma & Surgical Critical Care), R. Nierenberg (Emergency Medicine), M.
K. O’Brien (Anatomy), P. M. Opin (Dental), R. J. Parker (Dental), J. A.
Passarelli (Gastroenterology), M. F. Perkal (Gastroenterology), E. G. Polokoff
(Gastroenterology), R. P. Ponn (Cardiothoracic), T. Ponn (Gastroenterology),
M. R. Prete (Emergency Medicine), G. J. Price (Plastic), K. Restifo (Emergency
Medicine), D. D. Roberts (Otolaryngology), S. S. Rozen (Dental), E. C. Salk
(Emergency Medicine), J. C. Salomon (Plastic), R. F. Schlessel (Gastroenterology),
M. J. Schpero (Dental), S. Shah (Gastroenterology), R. K. Shaw (Cardiothoracic),
B. K. Singletary (Dental), J. A. Sirleaf (Emergency Medicine), M. K. Sonick
(Dental), R. E. Steller (Dental), G. Strothers (Otolaryngology), R. F. Stroup
(Urology), T. F. Sweeney (Vascular), J. M. Tan (Emergency Medicine), J. L. Tanenbaum
(Dental), A. Tarabar (Emergency Medicine), G. Terranova (Emergency Medicine),
S. C. Thornton (Gastroenterology), D. Tran (Trauma), R. Tross (Plastic), M.
B. Wallack (Dental), J. F. Walsh (Urology), H. K. Watson (Plastic), M. A. Wayne
(Emergency Medicine), M. H. Weinstein (Plastic), S. Weir (Emergency Medicine),
M. J. Werdmann (Emergency Medicine), A. E. Wilk (Dental), J. A. Wilkinson (Emergency
Medicine), J. M. Willett (Otolaryngology), K. Yanagisawa (Otolaryngology)
Clinical Instructors
P. W. Alberti (Otolaryngology), S. M. Ambrose (Emergency Medicine), J. P. Antoci
(Urology), J. A. Arons (Plastic), D. Ashmead IV (Plastic), D. Astrachan (Otolaryngology),
M. Azadpur (Dental), C. B. Beckman (Cardiothoracic), M. Beres (Otolaryngology),
J. S. Berkley (Dental), M. S. Bianchi (Otolaryngology), M. W. Bradway (Oncology),
E. Chen (Otolaryngology), B. Chervin (Otolaryngology), T. Coffey (Otolaryngology),
B. Cummings (Emergency Medicine), P. Demir (Urology), R. J. Devito (Urology),
S. M. Einbinder (Dental), R. A. Feldman (Urology), P. D. Fischer (Plastic),
M. J. Flanagan (Urology), P. L. Fortgang (Otolaryngology), R. A. Gaito (Otolaryngology),
S. Ganta (Gastroenterology), N. A. Gordon (Otolaryngology), M. Grushka (Otolaryngology),
I. Guttenberg (Otolaryngology), D. G. Hesse (Urology), R. J. Ippolito (Gastroenterology),
V. B. Khachane (Cardiothoracic), J. H. Klarsfeld (Otolaryngology), T. H. Lesnik
(Otolaryngology), R. A. Levin (Otolaryngology), M. Lin (Dental), J. R. Loeffler
(Otolaryngology), J. R. Lyons (Plastic), V. Mansourian (Gastroenterology), T.
V. Martin (Urology), R. J. Miles (Otolaryngology), S. Mitra (Otolaryngology),
A. J. Namon (Otolaryngology), W. J. Pite (Dental), V. Prabhat (Otolaryngology),
J. P. Roach (Urology), S. J. Salzer (Otolaryngology), J. F. Schmidt (Otolaryngology),
R. R. Sorrentino (Dental), E. M. Vining (Otolaryngology), T. W. Vris (Otolaryngology)
Postdoctoral Fellows
O. Araim (Vascular), A. Arjona (Neuropathology), C. E. Ariyan (Transplantation),
J. R. Borromeo (Vascular), Q. H. Chen (Vascular), R. Edwards (Cardiothoracic),
D. Eisenberg (Urology), A. G. Gallagher (Gastroenterology), A. Geirsson (Cardiothoracic),
D. S. Gortler (Vascular), A. O. Iakimov (Cardiothoracic), M. S. Kidd (Gastroenterology),
C. J. Lee (Plastic), T. S. Lee (Vascular), G. M. Maher (Urology), U. Marienfeld
(Neuropathology), E. S. Marques (Plastic), D. Martin-Escalante (Neuropathology),
S. J. Pak (Plastic), P. R. Salvalaggio (Transplantation), E. Sideridou (Administration),
Y. J. Su (Trauma & Surgical Critical Care), P. C. Tang (Cardiothoracic),
H. Ueno (Vascular), T. Yi (Transplantation), Q. C. Zhao (Trauma & Surgical
Critical Care)
Postdoctoral Associates
P. Afiatpour (Urology), Y. Bai (Cardiothoracic), W.-Z. Chang (Plastic), S. Kojima
(Anatomy), X.-X. Luo (Trauma), M. P. Parra (Plastic), S. Peng (Gross Anatomy),
K. Radebold (Gastroenterology), V. Rybalchenko (Otolaryngology), T. E. Stamkopoulos
(Gastroenterology), W. Takahashi (Urology), D. Zhang (Trauma & Surgical
Critical Care)
Lecturers
H. C. Briggs (Anatomy), E. Browne (Emergency Medicine), D. S. Cervonka (Emergency
Medicine), N. Collins (Plastic), A. Crovatto (Anatomy), E. Eisenberg (Dental),
B. C. Fichandler (Plastic), R. E. Fisher (Anatomy), S. Ghofrany (Gross Anatomy),
C. H. Jarmon (Emergency Medicine), S. E. Kapadia (Anatomy), L. G. Kelly (Emergency
Medicine), M. Kiessling (Emergency Medicine), M. Knobf (Internal Medicine),
D. S. MacMillan (Emergency Medicine), A. Meiman (Emergency Medicine), R. G.
Miller (Anatomy), M. Pineau (Trauma & Surgical Critical Care), P. Possenti
(Trauma & Surgical Critical Care), C. Powell (Otolaryngology), J. J. Roney
(Emergency Medicine), N. J. Smith (Otolaryngology), S. A. Wright (Emergency
Medicine), K. Yanagisawa (Otolaryngology)
Surgery 103, Surgical Clerkship. The twelve-week Surgery Clerkship is
divided into an eight-week block and a four-week block. The eight-week general
surgery core is consecutive and includes two four-week rotations. The clerkship
has been organized to expose students to the principles and practice of surgery,
engaging students in an ongoing dialogue focused on surgical problem solving.
General Surgery Core A: (Four weeks total) Students in the first clinical
year spend four weeks on the general surgery service of one of the following
hospitals: Yale-New Haven Hospital, Veterans Affairs Connecticut Health Care
System, West Haven, or Bridgeport Hospital. Staff.
General Surgery Core B: (Four weeks total) Students in the first clinical
year spend four weeks on the general surgery service of one of the following:
SICU/Anesthesia, CT/Vascular Surgery, Trauma/Emergency Medicine, or Hospital
of St. Raphael. Staff.
For the General Surgery Core A and Core B rotations, students can expect to be integrated into the clinical team and assigned to specific patients. Responsibilities include taking histories and performing physical examinations on their patients, participating in the evaluation and management of these patients, following patients' progress, and participating as assistants in the surgical operations performed upon their assigned cases. In addition, the students are expected to participate in the evaluation and care of outpatients seen in the clinics, the critically ill patient in the intensive care unit, and the injured patient in the emergency room. Emphasis is placed on involving students in the process of clinical problem solving with the guidance of the residents and the attending preceptors. A problem-oriented seminar series defines the core curriculum. A weekly case study seminar, directed by students, emphasizes the development of teaching skills.
General Surgery Core C: The four-week block may be taken independently
from the eight-week block and is devoted to the surgical specialties. Specialties
offered: orthopaedics, otolaryngology, pediatric surgery, plastic surgery, transplant
surgery, and urology. While on the specialty, the student is assigned patients
in rotation and carries out complete histories, physical examinations, and certain
procedures on these patients. The student is expected to participate, wherever
possible, in the operative procedures performed on these patients, and in postoperative
care. Students are also expected to attend the outpatient clinics in their assigned
specialty. Seminars covering all the specialties define the core curriculum.
Surgery 122, Subinternship, Plastic Surgery. Clinical experience as
an intern on a large clinical ward. The student has experience in the management
of craniofacial anomalies, burns, trauma, hand surgery, head and neck surgery,
reconstructive surgery of the head and neck and extremities, microsurgery, as
well as surgery of the congenital anomalies and cosmetic surgery. Limited to
one fourth-year student per month with a minimum of one-month rotations. Arrangements
must be made with J. A. Persing.
Surgery 123b, Biochemical and Metabolic Foundations of Plastic and Reconstructive
Surgery. A course designed to provide in-depth understanding of the molecular
events underlying the diverse clinical phenomena encountered in plastic surgery.
Topics include fluid electrolyte metabolism in the burn patient, biochemistry
and metabolism of collagen and its relation to scarring and connective tissue
disorders, normal wound healing, and disorders of the same. Offered for four
weeks during the spring term, two hours per week by arrangement. Limited to
two fourth-year students. J. A. Persing.
Surgery 129, Cardiopulmonary Transplantation. Intensive exposure to
laboratory and clinical aspects of cardiac, cardiopulmonary, and pulmonary transplantation.
Special emphasis on the relation between ongoing laboratory studies and clinical
practice in this field. Clinical involvement in preoperative assessment of prospective
transplant candidates, donor procurement, intraoperative management, and postoperative
immunosuppression. Limited to one student by arrangement with J. Elefteriades.
Surgery 130, Subinternship, Cardiothoracic. Intensive exposure to preoperative
and postoperative management of adult and pediatric cardiothoracic surgical
patients and to intraoperative conduct of surgical procedures, with active participation
in the operating room and in regular conferences. Students attend regular seminars
covering major areas of cardiothoracic surgery with members of the faculty,
and may be required to present a seminar on a subject in cardiothoracic surgery
to faculty and resident staff. Limited to two students in the second clinical
year. Three or six weeks by arrangement with J. Elefteriades.
Surgery 131, Subinternship, General Thoracic. Intensive exposure to
preoperative and postoperative management of general thoracic surgical patients
and to the intraoperative conduct of surgical procedures involving the lung,
the chest wall, the thymus, and the esophagus. Included is an organized lecture
series covering the entire field of general thoracic surgery. Students are expected
to present a seminar at the conclusion of the subinternship, focusing on a specialized
topic in general thoracic surgery. Six weeks by arrangement with J. Elefteriades.
Surgery 141, Outpatient Otolaryngology. This is an opportunity for those
students who have not had exposure in otolaryngology to spend time with a full-time
attending otolaryngologist seeing outpatients in an office setting. Timing is
quite flexible and a student may spend one to three mornings or afternoons each
week for one to four weeks. By arrangement with C. T. Sasaki and the full-time
otolaryngology staff.
Surgery 142, Emergency Medicine. The student participates in the evaluation
and treatment of adult emergency patients, learning appropriate work-up and
therapy. Students are expected to attend morning conferences four mornings per
week and to work four twelve-hour shifts that may include nights and weekends.
Prerequisite: Surgery 103.
Surgery 143, Care of the Intensive Care Unit Patient. Didactic and clinical
sessions in the Yale-New Haven Hospital SICU prepare the student to provide
basic treatment for the critically ill patient. Topics include cardiopulmonary
resuscitation, airway and ventilator management, assessment of the multiple
trauma patient, and management of sepsis. Prerequisite: Surgery 103. Three to
four weeks, by arrangement. R. Rabinovici, S. Rosenbaum.
Surgery 144, Trauma Surgery. The student functions as an extern and
participates actively in trauma service rounds, teaching conferences, trauma
resuscitation, and operative management of trauma cases. Students are expected
to attend conferences and take inhouse call with the chief resident of the trauma
service. Prerequisite: Surgery 103. R. Rabinovici.
Surgery 150, Plastic and Reconstructive Surgery. Evaluation and reconstructive
surgery of deformities of congenital, traumatic, and neoplastic origin. Includes
inpatient, outpatient, and operating room experience, supplemented by regular
conferences. Limited to two students; available throughout the year. J. A. Persing.
Surgery 151, Subinternship, General Surgery. (Four weeks) Offered throughout
the academic year at both Yale-New Haven Hospital and Veterans Affairs Connecticut
Health Care System, West Haven. Limited to second clinical year, one or two
students per month. Arrangements must be made with D. C. Andersen.
Surgery 152, Advanced Senior Seminar, General Surgery. This is a weekly
evening seminar series covering advanced and controversial topics in general
surgery. Three one-hour sessions include dinner at faculty homes and run from
October through February. Reprints of pertinent articles provided prior to each
seminar. Staff.
Surgery 153, Subinternship, Otolaryngology. This clinical experience
is independent of the third-year Surgery/Otolaryngology rotation, and takes
place on an individual basis. It includes operating room experience, ward responsibilities,
and involvement in outpatient ENT. Yale-New Haven Hospital, the Hospital of
St. Raphael, and the Veterans Affairs Connecticut Health Care System, West Haven,
are available for the rotation. Minimum rotation of four weeks; limited to one
student. J. F. Kveton, C. T. Sasaki.
Surgery 158, Surgery at Waterbury Hospital. A well-supervised fourth-year
clerkship including teaching rounds, operating room experience, outpatient clinical
experience, and conferences in radiology, pathology, oncology, vascular surgery,
and general surgery. Daily ICU rounds are conducted with an attending physician.
Six weeks, for one or two students, with room and meals provided. E. Kwasnik
and staff.
Surgery 159, Subinternship, Urology. Varied clinical studies, in-depth
experience in all forms of urology. Limited to clinical years. One student per
month, for three to four weeks. R. Weiss and staff.
Surgery 160, Surgery at St. Mary's Hospital, Waterbury. Six-week subinternship
in an affiliated community hospital of 400 beds, consisting of ward and operative
experience, teaching rounds, and conferences. An independent general surgical
residency exists at St. Mary's. S. Dudrick and staff.
Surgery 165, Surgery at Bridgeport Hospital. For a student contemplating
a career in clinical surgery, an opportunity to function as a team member with
residents and attending staff in a large community hospital. General surgery
with fundamental pre- and postoperative care, appropriate operating room activity,
basic bedside diagnostic and therapeutic hands-on experience, emphasis on intensive
care unit, trauma, and burns. Each student is expected to present a twenty-minute
research or clinical topic of choice at completion of the course. Room and board
available on duty. Limited to one or two students for six- to eight-week rotations
in the fourth year. Staff.
Surgery 171, Subinternship, Peripheral Vascular Surgery. A practical
experience in the diagnosis and management of vascular disease, including pre-
and postoperative care. The scope of the experience includes orientation to
the noninvasive vascular diagnostic laboratory, outpatient care in the Yale
Vascular Center, and inpatient management (including patients in the OR, ICU,
and the vascular surgery unit). Four weeks, by arrangement with B. Sumpio and
staff.
Surgery 172, Subinternship, Transplantation Surgery. This intensive
clinical experience emphasizes the preoperative assessment, intraoperative care,
and postoperative management of patients suffering end-stage organ system failure
who are cared for by transplantation. Emphasis also includes the management
of immunosuppressive medication regimens and the care of post-transplant problems.
Available throughout the year, one or two students, for one month. Arrangements
with M. Lorber and staff.
Surgery 173, Experimental Transplantation Surgery and Immunobiology.
Clinical and laboratory studies into problems relevant to the field of organ
transplantation. Students work under the tutelage of a member of the faculty
in the Division of Organ Transplantation. Original projects must be mutually
agreed upon, and may include studies into the immunology of allograft rejection,
the mechanism of immunosuppressive drug action, immunological monitoring of
patients following transplantation, or biochemical markers to potentially identify
early rejection of renal, hepatic, pancreatic, or small bowel allografts. Available
throughout the year, one or two students, time commitment by arrangement. M.
Lorber and staff.
Surgery 174, Subinternship in Surgical Oncology. Intensive exposure
to surgical aspects of the treatment of cancer in clinic, hospital, and operating
room. The interaction between surgery, medical oncology, and radiation therapy
is experienced by following patients receiving multiple forms of therapy. Available
throughout the year, one or two students, preferably for one-month rotations.
Arrangements with R. R. Salem.
Surgery 175, Pediatric Cardiac Surgery. Intensive exposure to pediatric
cardiac surgery with emphasis on preoperative evaluation and postoperative management.
The student observes the changes in pre- and postoperative physiology and spends
much of the time following postoperative patients. The student is exposed to
the use of ventilators in the pediatric patient, inotropic and vaso-dilating
agents, evaluation and treatment of low cardiac output state, and the use of
pacemakers. Weekly conferences include surgical conferences, preoperative conferences,
catheterization conference, pre- and postoperative clinics, as well as weekly
sessions with the attending staff. Some technical experience and instruction
are provided in the operating room according to the student's interest. Limited
to one student per month except August, September, and December. G. S. Kopf
and staff. Arrangements to be made with G. Kopf.
Surgery 176, Subinternship in Pediatric Surgery. In-depth exposure to
the broad spectrum of pediatric surgical problems of the abdomen, chest, head
and neck, and pelvis. The student obtains experience with correction of congenital
anomalies, management of trauma, care of the critically ill child, and management
of solid tumors. The subintern is an integral part of the pediatric surgical
team and is expected to take in-house night call every third night. Contact
R. Touloukian.
Therapeutic Radiology
Office: HRT 140, 785.2956
Professors
D. Brash, J. J. Fischer (Chair), P. M. Glazer, B. G. Haffty, B. M. Kacinski,
R. Nath (Physics), R. E. Peschel, S. C. Rockwell, W. D. Rupp, R. J. Schulz (Emeritus),
Y. H. Son, W. C. Summers
Professor of Research
K. B. Low (Adjunct)
Associate Professors
S. J. Baserga, F. d’Errico, J. Knisely, K. B. Roberts, J. Sweasy, L. D.
Wilson
Assistant Professors
Z. Chen, S. Higgins, D. Kim, M. Moran, N. Yue
Research Scientists
D. B. Fischer, E. Sapi
Associate Research Scientists
M. Flick, M. Gilmore-Hebert, P. Havre, B. King
Research Affiliate
W. P. Summers
Associate Clinical Professors
A. H. Knowlton, P. Pathare
Postdoctoral Fellows
A. Alvero, P. Compagnone-Post, L. Gorman, T. Gorton, D. Roa, F. Rogers, S. Takeuchi
Postdoctoral Associates
P. Fotiadou, A. Khan, T. Lang, M. Maitra, V. Mihaylova, W. Zhang
Lecturers
J. Bond, R. Vera
Therapeutic Radiology 101, Clinical Clerkship in Radiation Therapy.
A flexible program designed to introduce the medical student to radiation therapy.
The biological and physical bases of radiation therapy, together with clinical
practice and ongoing research. Clinical exposure to patients with malignant
disease, with between seventy and one hundred treated daily in the department.
The student takes part in departmental conferences, clinics, lectures, and individual
teaching sessions. Limited to two students at any time. B. G. Haffty and staff.
Therapeutic Radiology 102, Clinical Radiobiology. This course is designed
to provide residents in radiation oncology with a comprehensive review of clinical
radiobiology as it applies to the practice of radiation therapy. The course
is open to residents and fellows in other disciplines interested in radiobiology
as it applies to clinical oncology. The course participant attends approximately
twenty lectures in clinical radiobiology, which are delivered throughout the
academic year between September and June. Scheduling by arrangement with B.
G. Haffty.
Therapeutic Radiology 201b, A Survey of Radiobiology. A review of the
interaction of radiation on living organisms, progressing from DNA damage to
complex mammalian systems. Modern concepts in molecular biology and cell kinetics
are emphasized in understanding the sequelae of this interaction and the mechanism
by which the organism responds to the injury produced. Fourteen sessions. By
arrangement with Radiobiology staff.
Therapeutic Radiology 305, Principles and Methods of Radiation Dosimetry.
A graduate-level course for physics students or medical students with a strong
physics background who want to learn about radiation dosimetry as it applies
to medical practice. Topics include X-ray spectra, ionization chambers, X-ray
exposure and the roentgen, mass energy-absorption coefficients, the Bragg-Gray
principle, stopping power and linear energy transfer, chemical dosimeters, instrumentation,
and physical aspects of radiology. Approximately twenty hours of tutorial sessions.
Scheduling by arrangement with instructor. R. Nath.
Therapeutic Radiology 306, Laboratory Projects in Radiation Dosimetry.
Students are given problems that relate to and supplement long-term, ongoing
radiation dosimetry projects within the department. Prerequisite: Therapeutic
Radiology 305, or its equivalent. Scheduling by arrangement with instructor.
R. Nath.
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