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Aptamers and Allosteric Ribozymes | Riboswitches | Tutorials
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The Breaker Laboratory at Yale University is part of a community of researchers exploring the structural and functional capabilities of natural and engineered nucleic acids. Our research currently is divided among five main areas. The links below connect to short descriptions of the highlights of each area with additional links to literature citations.
Deoxyribozymes Beyond the double helix – DNAs that work as enzymes
Ribozymes Expanding the diversity of RNA enzymes.
Enzyme Speed Limits Catalytic mechanisms of ribozymes, deoxyribozymes, and protein enzymes.
Aptamers and Allosteric Ribozymes Engineering new RNAs as molecular switches.
Riboswitches RNA genetic control elements that bind metabolites.

View our tutorials:
We invite scientists from other fields, instructors at all levels, and interested members of the public to learn the basic principles of our science.

Functional Nucleic Acids
RNA as a Living Molecule
In Vitro Evolution
Nucleic Acid Engineering


 

 


Email: Ronald Breaker

Office: (203) 432-9389
Lab: (203) 432-6554
Fax: (203) 432-6161
 
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